基于龈沟液炎症因子水平及牙齿咬合功能探讨无托槽隐形矫治与固定矫治对错[牙合]畸形患者的治疗效果  

Based on the level of inflammatory factors in gingival crevicular fluid and the occlusal function of teeth,the effect of invisible and fixed correction without brackets on the patients with malocclusion deformity

作　　者：赵珍 古力巴哈·买买提力 张娟娟 刘博 Zhao Zhen;Gu-li-ba-ha·Mai-mai-ti-li;Zhang Juan-juan;Liu Bo(Department of Stomatology,Yongcheng People's Hospital,Shangqiu 476600,Henan,China;Department of Stomatology,The Second Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,China;Department of Stomatology,Yongcheng Stomatological Hospital,Shangqiu 476600,Henan,China)

机构地区：[1]永城市人民医院口腔科,河南商丘476600 [2]新疆医科大学第二附属医院口腔科,新疆乌鲁木齐830000 [3]永城市口腔医院口腔科,河南商丘476600

出　　处：《四川生理科学杂志》2024年第7期1421-1424,1469,共5页

基　　金：河南省医学科技攻关联合共建项目(编号:LHGJ20221039)。

摘　　要：目的:对比无托槽隐形矫治与固定矫治错[牙合]畸形患者的治疗效果及对龈沟液炎症因子水平、牙齿咬合功能的影响。方法:回顾性收集我院2021年5月至2023年5月收治的92例错[牙合]畸形患者的病例资料,按手术方案不同分为两组(n=46),观察组接受无托槽隐形矫治,对照组接受固定矫治。对比两组患者矫治6m后矫治效果;矫治前、矫治3 m、6 m后牙周健康指标,包括牙龈指数(Gingival index,GI)、龈沟出血指数(Sulcus bleeding index,SBI)、菌斑指数(Plaqueindex,PLI)、牙周探诊深度(Periodontaldepth,PD)以及并发症发生率,并采用Tee Tester咬合力检测仪检测矫治前、矫治3 m、6 m后牙齿咬合功能([牙合]力总值、[牙合]力中心点最大位移、[牙合]力不对称指数),采用酶联免疫吸附试验检测矫治前、矫治3 m、6 m后龈沟液炎症因子,如白细胞介素-6(Interleukin-6,IL-6)、可溶性细胞间粘附分子-1(Soluble intercellular adhesion molecule-1,sICAM-1)、白细胞介素-1β(Interleukin-1β,IL-1β)水平。结果:观察组总有效率97.83%(45/46)相较于对照组78.26%(36/46)更高(P<0.05);与矫治前相比,各治疗组的GI、SBI、PLI、PD均明显降低(P<0.05),其中观察组更为显著(P<0.05);与矫治前相比,各治疗组的[牙合]力总值均明显升高,[牙合]力中心点最大位移、[牙合]力不对称指数均明显降低,其中观察组更为显著(P<0.05);与矫治前相比,各治疗组的龈沟液IL-6、sICAM-1、IL-1β水平均明显升高,其中对照组更为显著(P<0.05);观察组并发症发生率4.35%(2/46)相较于对照组21.74%(10/46)更低(P<0.05)。结论:经无托槽隐形矫治错[牙合]畸形患者整体矫治效果优于固定矫治。Objective:To compare the therapeutic effects of invisible correction without brackets and fixed correction on the levels of inflammatory factors in gingival crevicular fluid and the occlusal function of teeth in patients with malocclusion deformity.Methods:Retrospectively collected the case data of 92 patients with malocclusion who were admitted to our hospital from May 2021 to May 2023.The patients were divided into two groups according to the different surgical plans(n=46).The observation group received invisible orthodontics without brackets,while the control group received fixed orthodontics.The treatment effects of the two groups were compared after six months of treatment.Before treatment,after three months,and after six months of treatment,the periodontal health indicators including gingival index(GI),sulcus bleeding index(SBI),plaque index(PLI),periodontal depth(PD),and complication rate were measured.The Tee Tester bite force detector was used to measure the teeth'bite function,such as the total value of occlusal force,maxim assume displacement of occlusal force center point,and asymmetric index of occlusal force.The enzyme-linked immunosorbent assay was used to detect the inflammatory factors levels in the gingival crevicular fluid,such as interleukin-6(IL-6),soluble intercellular adhesion molecule-1(sICAM-1),and interleukin-1β(IL-1β).Results:The total effective rate of the observation group was 97.83%(45/46),which was higher than the 78.26%(36/46)in the control group(P<0.05).Compared with before orthodontic treatment,the GI,SBI,PLI,and PD in each treatment group were significantly decreased(P<0.05),and the observation group was more significant(P<0.05).Compared with before orthodontic treatment,the total value of the occlusal force in each treatment group was significantly increased,the maximum displacement of the occlusal force center point and the asymmetry index of the occlusal force was significantly decreased,and the observation group was more significantly(P<0.05).Compared with before orthodont

关 键 词：无托槽隐形矫治 错[牙合]畸形 龈沟液炎症因子 固定矫治 牙齿咬合功能 

分 类 号：R783.5[医药卫生—口腔医学]