改良保留灌肠术与传统保留灌肠术治疗急性胰腺炎合并PI患者的效果对比  

Comparison of the effect of modified retention enema and traditional retention enema in the treatment of acute pancreatitis with PI

作　　者：魏雪静 刘璐 裴佳佳 高倩倩 Wei Xue-jing;Liu Lu;Pei Jia-jia;Gao Qian-qian(Out-patient Department,The First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,Henan,China;Department of Gynecology,The First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,Henan,China;Department of Neurology,The First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,Henan,China;Department of Gastrointestinal Surgery,The First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,Henan,China)

机构地区：[1]河南科技大学第一附属医院门诊部,河南洛阳471000 [2]河南科技大学第一附属医院妇科,河南洛阳471000 [3]河南科技大学第一附属医院神经内科,河南洛阳471000 [4]河南科技大学第一附属医院胃肠外科,河南洛阳471000

出　　处：《四川生理科学杂志》2024年第7期1507-1510,共4页

摘　　要：目的:探究改良保留灌肠术与传统保留灌肠术治疗急性胰腺炎合并麻痹性肠梗阻(Paralytic Ileus,PI)患者的效果。方法:选取2022年1月至2023年1月于我院急诊外科就诊的87例急性胰腺炎合并PI的患者作为研究对象,按照随机数表法分为传统组(n=43)和改良组(n=44)。传统组采用传统保留灌肠术进行治疗,改良组采用改良保留灌肠术进行治疗。观察两组患者治疗效果、临床指标、胃肠道功能情况及舒适度。结果:改良组的治疗有效率和舒适度的优良率均明显高于传统组(P<0.05)。与传统组进行比较,改良组腹胀缓解、腹痛缓解、首次排气、首次排便及肠鸣音恢复所用时间均明显更短(P<0.05)。改良组干预1 w后的血清胃动素、胃泌素及血管活性肠肽水平明显高于传统组(P<0.05)。结论:改良保留灌肠术治疗急性胰腺炎合并PI患者的临床效果显著,可快速患者腹胀、腹痛症状,加快患者胃肠功能的恢复速度,改善胃肠激素水平,且舒适度较高。Objective:To explore the effects of modified retention enema and traditional retention enema in the treatment of Paralytic Ileus(PI)patients with acute pancreatitis.Methods:A total of 93 patients with acute pancreatitis combined with PI who were treated in the emergency surgery department of our hospital from January 2022 to January 2023 were selected,6 cases fell off halfway,and 87 cases were finally enrolled in the study.They were divided into the traditional group(43 cases)and the improved group(44 cases)according to random number table method.The traditional group was treated with traditional retention enema,and the improved group was treated with modified retention enema.The therapeutic effect,clinical indexes,gastrointestinal function and comfort level of the two groups were observed.Results:The effective rate and the comfort rate of the improved group were significantly higher than those of the traditional group(P<0.05).Compared with the traditional group,the time of abdominal distension relief,abdominal pain relief,first exhaust,first defecation and bowel sound recovery in the improved group was significantly shorter,and the difference was statistically significant(P<0.05).After 1 week of intervention,the levels of serum motilin,gastrin and vasoactive intestinal peptide in the improved group were significantly higher than those in the traditional group,and the differences were statistically significant(P<0.05).Conclusion:Modified retention enema in the treatment of acute pancreatitis with PI has significant clinical effects,which can accelerate the symptoms of abdominal distension and abdominal pain,accelerate the recovery of gastrointestinal function,improve gastrointestinal hormone levels,and have a high comfort level.

关 键 词：急性胰腺炎 麻痹性肠梗阻 保留灌肠术 柴芩承气汤 胃肠功能 

分 类 号：R576[医药卫生—消化系统]