卡络磺钠联合血凝酶在急性上消化道出血治疗中的应用  

Application of carbazol sodium sulfonate combined with hemagglutinin in the treatment of acute upper gastrointestinal bleeding

作　　者：刘春侠 Liu Chun-xia(Xiayi Second People's Hospital Western Pharmacy,Xiayi 476400,Henan,China)

机构地区：[1]夏邑县第二人民医院西药房,河南夏邑476400

出　　处：《四川生理科学杂志》2024年第7期1565-1566,1607,共3页

摘　　要：目的:分析急性上消化道出血经卡络磺钠联合血凝酶治疗的效果。方法:选取2020年1月至2023年10月期间本院收治的76例急性上消化道出血患者作为研究对象,采用随机数字表法将患者分为对照组和观察组,各38例。对照组采用血凝酶常规治疗,观察组在对照组基础上增加采用卡络磺钠治疗,两组均连续治疗3 d。分析比较两组止血时间、住院时间、凝血功能、不良反应发生情况。结果:治疗后,观察组止血时间、住院时间均明显短于对照组(P<0.05);观察组纤维蛋白原均明显高于对照组、活化部分凝血活酶时间和凝血酶原时间均明显短于对照组(P<0.05)。两组不良反应发生率无明显差异(P>0.05)。结论:卡络磺钠联合血凝酶能够在短时间内帮助急性上消化道出血患者止血,改善凝血功能,促进患者康复,减少住院时间,且具有较高的治疗安全性。Objective:To analyze the effect of carbazol sodium sulfonate combined with hemagglutinin in the treatment of acute upper gastrointestinal hemorrhage.Methods:A total of 76 patients with acute upper gastrointestinal hemorrhage admitted to our hospital from January 2020 to October 2023 were selected as the research objects.The patients were divided into control group and observation group by random number table method,with 38 cases in each group.The control group received routine treatment with hemagglutinin,and the observation group received additional treatment with sodium carbosulfonate on the basis of the control group.Both groups received continuous treatment for 3 days.The hemostatic time,hospital stay,coagulation function and adverse reactions of the two groups were analyzed and compared.Results:After treatment,the hemostatic time and hospitalization time of observation group were significantly shorter than that of control group(P<0.05).The fibrinogen time of observation group was significantly higher than that of control group,and the activated partial thromboplastin time and prothrombin time were significantly shorter than that of control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Carbazol sodium sulfonate combined with hemagglutinin can help patients with acute upper gastrointestinal hemorrhage to stop bleeding in a short period of time,improve coagulation function,promote patient rehabilitation,reduce hospital stay,and has a high therapeutic safety.

关 键 词：卡络磺钠 血凝酶 急性上消化道出血 临床疗效 凝血功能 

分 类 号：R573.2[医药卫生—消化系统]