前葡萄膜炎中医证素特点研究  

Study on Traditional Chinese Medicine Syndrome Elements Characteristics of Ante-rior Uveitis

作　　者：毕徐齐 朱笑莹 杨永升[1] BI Xuqi;ZHU Xiaoying;YANG Yongsheng(Eye Hospital,China Academy of Chinese Mecical Sciences,Beijing 100040,China)

机构地区：[1]中国中医科学院眼科医院,北京100040

出　　处：《中国中医眼科杂志》2024年第8期742-747,共6页China Journal of Chinese Ophthalmology

基　　金：中国中医科学院眼科医院高水平中医医院课题(GSP2-13)。

摘　　要：目的研究与总结前葡萄膜炎(AU)中医证素特点,为AU的规范临床辨证论治提供参考。方法收集中国知网、万方、维普数据库从建库至2023年3月31日正式发表的关于AU中医证型的相关文献,对中医证名进行规范化处理以及证型的拆解,将文献中筛选出的证型条目及病例数归纳建立Excel软件数据库。对病位证素及病性证素进行频数、频率描述分析,对证素进行系统聚类分析和关联规则分析。结果(1)一般情况:纳入文献24篇,总病例数1,685例。(2)证型及证素分布:频率排名前5位的证型有肝经风热证(329次,19.53%)、肝胆火炽证(224次,13.29%)、肝火炽盛证(205次,12.17%)、阴虚火旺证(166次,9.85%)、肝胆湿热证(94次,5.58%)。(3)证素特点:病位证素有5个,以频率从高到低排名依次是肝(1,035次,61.42%)、胆(335次,19.88%)、表(163次,9.64%)、肾(117次,6.94%)、脾(55次,3.26%)。病性证素类型共13种,热病性出现频次最高,为1,447次(85.88%)。以虚性、实性进行分类分析,实性证素共出现了2,458次(76.42%),虚性证素共出现了758次(23.56%);其中,热证素在实性证素中出现频次最高,共1,447次(44.99%);阴虚证素在虚性证素中出现频次最高,共374次(11.63%)。(4)证素关联规则分析:共得到8条强关联规则,其中二项强关联规则5个,三项强关联规则3个,推断出5个基础证候,分别为肝火炽盛证、风热证、湿热证、肝胆火炽证、肝经风热证。关联规则网状图显示肝与热的关联最强,推断基础证候为肝火炽盛。结论肝经风热、肝胆火炽、肝火炽盛3个证型是前葡萄膜炎患者的主要证型。前葡萄膜炎的重要病位证素为肝,重要病性证素为热,病性特点以实证为主。OBJECTIVE To investigate and summarize the characteristics of syndrome elements of anterior uveitis(AU)in Traditional Chinese Medicine(TCM)literature,providing references for standardized clinical syndrome differentiation and treatment of AU.METHODS Relevant TCM syndrome type literature on AU published in CNKI,Wanfang,and VIP databases from their inception to March 31st,2023,was collected.TCM syndrome names were standardized and the syndromes were deconstructed.The syndrome entries and case numbers extracted from the literature were compiled into an Excel database.Frequency and frequency descriptive analyses were conducted on disease location and disease nature syndrome elements.Systematic cluster analysis and association rule analysis were performed on the syndrome elements.RESULTS(1)General information:A total of 24 articles were included,with a total of 1,685 cases.(2)Distribution of syndromes and syndrome elements:The top five syndromes were liver meridian windheat(329 times,19.53%),excessive liver-gallbladder fire(224 times,13.29%),hyperactivity of liver fire(205 times,12.17%),Yin deficiency with effulgent fire(166 times,9.85%),and damp-heat in liver and gallbladder(94 times,5.58%).(3)Characteristics of syndrome elements:There were five disease location elements,ranked by frequency:Liver(1,035 times,61.42%),gallbladder(335 times,19.88%),exterior(163 times,9.64%),kidney(117 times,6.94%),and spleen(55 times,3.26%).There were 13 types of disease nature elements,with heat being the most frequent(1,447 times,85.88%).In the classification analysis of deficiency and excess,excess syndrome elements appeared 2,458 times(76.42%),while deficiency syndrome elements appeared 758 times(23.56%).Among excess syndrome elements,heat was the most frequent(1,447 times,44.99%),and Yin deficiency was the most frequent among deficiency syndrome elements(374 times,11.63%).(4)Association rule analysis of syndrome elements:Eight strong association rules were identified,including five two-item strong association rules and three three-

关 键 词：前葡萄膜炎 证素 辨证论治 文献研究 

分 类 号：R773[医药卫生—眼科] R276.7[医药卫生—临床医学]