儿童癫痫持续状态52例预后分析  

Prognostic Analysis of 52 Cases of Status Epilepticus in Children

作　　者：高宇 苏学文 GAO Yu;SU Xuewen(Inner Mongolia University of Science and Technology Baotou Medical College,Baotou 014040 China;Department of Pediatrics,People's Hospital of Inner Mongolia Autonomous Region,Hohhot 010017 China)

机构地区：[1]内蒙古科技大学包头医学院,内蒙古包头014040 [2]内蒙古自治区人民医院儿科,呼和浩特010017

出　　处：《内蒙古医学杂志》2024年第6期693-697,共5页Inner Mongolia Medical Journal

摘　　要：目的探讨呼和浩特及周边地区癫痫持续状态患儿的临床特点及其中各种因素对预后的影响。方法回顾性分析2016年1月至2023年8月于内蒙古自治区人民医院确诊的52例癫痫持续状态患儿的临床资料,根据随访情况分为预后良好组与预后不良组,并对比各因素对预后的影响。结果本研究纳入的52例患儿中,67.3%的病因为症状性癫痫,其中以急性病因占多数;另有32.7%为原发性癫痫。两组患儿中,预后良好的患儿33例(63.5%),预后不良的患儿19例(36.5%)。两组患儿性别、年龄、诱因、既往惊厥史、癫痫持续状态类型及影像学检查等因素比较差异无统计学意义(P>0.05);病因、惊厥持续时间、用药至惊厥发作停止时间及床旁脑电监测比较差异有统计学意义(P<0.05)。结论病因、惊厥持续时间、用药至惊厥发作停止时间、床旁脑电监测均可能对预后造成重要的影响。Objective To explore the characteristics of clinical data of children with persistent status epilepticus in Hohhot and surrounding areas of Inner Mongolia and the influence of various factors on prognosis among them.Methods The clinical data of 52 children with persistent status epilepticus who were clearly diagnosed in the People's Hospital of Inner Mongolia Autonomous Region from January 2016 to August 2023 were retrospectively analyzed,divided into good prognosis group and bad prognosis group according to the follow-up,and compared the effects of various factors on prognosis.Results Of the 52 children included in this study,67.3%had symptomatic etiology,with acute etiology accounting for the majority,and another 32.7%had primary epilepsy.Of the children in both groups,33(63.5%)had a favorable prognosis and 19(36.5%)had a poor prognosis.There was no statistically significant difference between the two groups in terms of gender,age,triggers,previous history of convulsions,type of status epilepticus,and imaging examination(P>0.05),and there was a statistically significant difference in terms of etiology,duration of convulsions,medication to seizure cessation time,and bedside electroencephalogram(EEG)monitoring(P<0.05).Conclusion Etiology,duration of convulsions,time from medication to cessation of convulsive seizures,and bedside EEG monitoring may have a significant impact on prognosis.

关 键 词：癫痫持续状态 病因 脑电监测 预后 

分 类 号：R742.1[医药卫生—神经病学与精神病学]