胃癌患者腹腔镜手术治疗中根治术的应用对肿瘤标志物及并发症的影响  

Impact of Radical Laparoscopic Surgery in Gastric Cancer Patients on Tumor Markers and Postoperative Complications

作　　者：冯闵 朱焕明[1] 谢荣兵 FENG Min;ZHU Huan-ming;XIE Rong-bing(Macheng People's Hospital,Macheng,438300,Hubei)

机构地区：[1]麻城市人民医院,湖北麻城438300

出　　处：《黔南民族医专学报》2024年第2期139-142,共4页Journal of Qiannan Medical College for Nationalities

摘　　要：目的:针对胃癌患者的治疗,分析腹腔镜下根治术对于肿瘤标志物及并发症产生的影响作用。方法:将在麻城市人民医院行手术治疗胃癌患者,共计有64例,分组基于术式的差异分为腹腔镜组、开腹组,对两组患者的治疗结果进行比较。结果:与开腹组比较,腹腔镜组手术持续时间长,并且具有更少的术中出血量,缩短了患者的住院持续时间(P<0.05)。此外,实施腹腔手术,患者独自下床活动时间更短,患者术后拔除引流管时间以及手术治疗后首次肛门排气时间均更短(P<0.05);在术前,对比两组患者CEA、CA724水平,差异很少(P>0.05),分别于术后3个月、6个月测定两组CEA、CA724水平发生的变化,结果显示均下降(P<0.05),同时腹腔镜组上述指标发生更为明显的变化;此外,术后腹腔镜组具有更低的并发症发生率(P<0.05)。结论:针对胃癌患者的治疗,腹腔镜根治术术后恢复快,能够降低肿瘤标志物水平,减少并发症。Objective:To evaluate the impact of laparoscopic radical resection on tumor markers and postoperative complications in the treatment of gastric cancer patients.Methods:A total of 64 gastric cancer patients who underwent surgical treatment at Macheng People's Hospital were grouped based on surgical approach into a laparoscopic group and an open surgery group.Comparative analyses were performed on the therapeutic outcomes between the two groups.Results:Compared with the open surgery group,the laparoscopic group had longer operation durations,less intraoperative blood loss,and shorter hospital stays(P<0.05).Moreover,laparoscopic surgery patients had shorter times to independent ambulation,earlier removal of drainage tubes,and faster recovery of bowel function as evidenced by earlier first flatus after surgery(P<0.05).Preoperatively,there was minimal difference in CEA and CA724 levels between the groups(P>0.05).However,at 3 and 6 months postoperatively,both CEA and CA724 levels decreased in both groups(P<0.05),with more prominent reductions observed in the laparoscopic group.Furthermore,the laparoscopic group experienced a lower rate of postoperative complications(P<0.05).Conclusion:For gastric cancer treatment,laparoscopic radical resection offers faster recovery,reduction in tumor marker levels,and a decrease in complication incidence.

关 键 词：腹腔镜 根治术 胃癌 肿瘤标志物 并发症 

分 类 号：R735.2[医药卫生—肿瘤]