高活性骨替代材料在颌面部骨组织工程中的应用进展  

Research progress of application of highly active bone substitute in materialsmaxillofacial bone tissue engineering

作　　者：袁露函 楚晨 袁荣涛 YUAN Lu-han;CHU Chen;YUAN Rong-tao(School of Stomatology,Qingdao University,Qingdao 266003;Department of Stomatology,Qingdao Municipal Hospital&Qingdao Hospital of Rehabilitation University,Qingdao 266071,Shandong Province,China)

机构地区：[1]青岛大学口腔医学院,山东青岛266003 [2]青岛市市立医院(康复大学青岛医院)口腔医学中心,山东青岛266071

出　　处：《中国口腔颌面外科杂志》2024年第4期394-399,共6页China Journal of Oral and Maxillofacial Surgery

摘　　要：颌骨缺损是口腔颌面外科最常见的疾病之一,严重颌骨缺损会对患者生活和心理造成不同程度的影响,需要进行及时有效的修复。颌骨具有的独特生理外形和个体差异,导致颌骨缺损的修复无法完全依赖于标准化的骨修复体。随着相关制造技术的发展和成熟,特别是3D打印技术在骨缺损修复方面具有的独特优势,已引起国内外学者广泛关注。骨缺损修复是一个复杂而精密的过程,理想的修复骨缺损的生物材料应具备良好的组织相容性、合适的机械应力、适宜的孔径大小和溶解性等特性。本文简要综述了现有的用于颌骨组织工程的高活性骨替代材料。Jaw defect is one of the most common diseases in oral and maxillofacial surgery.Severe jaw defect will cause different degrees of impact on the life and psychology of patients,and needs timely and effective repair.Due to the unique physiologic appearance and individual differences of jaw bones,the repair of jaw defects can't be completely depen-dent on standardized bone prosthetics.With the development and maturity of related manufacturing technologies,especial-ly the unique advantages of 3D printing technology in bone defect repair,it has attracted wide attention of scholars both at home and abroad.The repair of bone defects is a complex and precise process.The ideal biomaterials for repairing bone defects should have good histocompatibility,suitable mechanical stress,suitable pore size,and solubility.This article briefly reviewed the existing high-active bone replacement materials for jaw tissue engineering.

关 键 词：颌骨 生物材料 组织工程 颌骨缺损 3D打印 

分 类 号：R782.2[医药卫生—口腔医学]