经口腔前庭颈部正中路径完全腔镜下甲状腺切除手术治疗甲状腺乳头状癌的效果  

Effect of Complete Endoscopic Thyroidectomy via Oral Vestibulo Neck Median Route in the Treatment of Papillary Thyroid Carcinoma

作　　者：谢伟 梁文杰 黎然 XIE Wei;LIANG Wenjie;LI Ran(Yangjiang People's Hospital,Yangjiang 529500,China;不详)

机构地区：[1]阳江市人民医院,广东阳江529500

出　　处：《中外医学研究》2024年第20期9-12,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

基　　金：广东省阳江市医疗卫生科技计划项目(SF2021029)。

摘　　要：目的:探讨经口腔前庭颈部正中路径完全腔镜下甲状腺切除手术治疗甲状腺乳头状癌的效果。方法:选取2021年5月—2023年5月阳江市人民医院收治的98例甲状腺乳头状癌患者作为研究对象。根据随机数表法将其分为对照组(n=49)与试验组(n=49)。对照组给予开放式甲状腺切除术,试验组给予经口腔前庭颈部正中路径完全腔镜下甲状腺切除手术。比较两组围手术期指标,术前及术后1周吞咽功能及生活质量,术前、术后72 h、术后14 d疼痛程度,并发症。结果:试验组术后住院时间短于对照组,术中出血量少于对照组,差异有统计学意义(P<0.05)。术后1周,两组标准吞咽功能评价量表(SSA)评分降低,健康调查简表(SF-36)评分升高,试验组SSA评分低于对照组,SF-36评分高于对照组,差异有统计学意义(P<0.05)。术后72 h、14 d,两组视觉模拟评分法(VAS)评分高于术前,试验组VAS评分低于对照组,术后14 d,两组VAS评分低于术后72 h,差异有统计学意义(P<0.05)。重复测量方差分析结果显示,两组术前、术后72 h、术后14 d VAS评分组间、时间、交互作用比较,差异有统计学意义(P<0.05)。两组并发症发生率比较,差异无统计学意义(P>0.05)。结论:经口腔前庭颈部正中路径完全腔镜下甲状腺切除手术应用于甲状腺乳头状癌患者可减轻手术创伤,对吞咽功能影响小,可减轻疼痛。Objective:To explore the effect of complete endoscopic thyroidectomy via oral vestibulo neck median route in the treatment of papillary thyroid carcinoma.Method:Ninety-eight patients with papillary thyroid carcinoma admitted to Yangjiang People's Hospital from May 2021 to May 2023 were selected as the study objects.They were divided into control group(n=49)and experimental group(n=49)according to random number table method.The control group was given open thyroidectomy,and the experimental group was given complete endoscopic thyroidectomy via oral vestibulo neck median route.The perioperative indexes,swallowing function and quality of life before surgery and one week after surgery,pain degree before surgery,72 h after surgery and 14 d after surgery and complications of the two groups were compared.Result:The postoperative hospitalization time of experimental group was shorter than that of control group,and the intraoperative blood loss volume was less than that of control group,the differences were statistically significant(P<0.05).At 1 week after surgery,the standard swallowing function assessment scale(SSA)scores decreased in both groups,while the health survey brief form(SF-36)scores increased,the SSA of the experimental group was lower than that of the control group,the SF-36 score was higher than that of the control group,and the differences were statistically significant(P<0.05).At 72 h and 14 d after surgery,the visual analogue scale(VAS)scores of the two groups were higher than those before surgery,while the VAS scores of the experimental group were lower than those of the control group;on 14 d after surgery,the VAS scores of the two groups were lower than that 72 h after surgery,and the differences were statistically significant(P<0.05).The results of repeated measurement analysis of variance showed that there were statistically significant differences between groups,time and interaction of VAS before surgery,72 h and 14 d after surgery(P<0.05).There was no significant difference in the incidence of comp

关 键 词：经口腔前庭颈部正中路径 完全腔镜下甲状腺切除手术 开放式甲状腺切除术 吞咽功能 

分 类 号：R736.1[医药卫生—肿瘤]