后腹腔镜辅助小切口保留肾单位手术治疗肾癌患者的疗效及术后复发危险因素分析  

Analysis of the Efficacy and Postoperative Recurrence Risk Factors of Posterior Laparoscopic-assisted Small-incision Kidney Unit-preserving Surgery in Patients with Renal Cancer

作　　者：杨洋[1] 詹永豪 YANG Yang;ZHAN Yonghao(The First Affiliated Hospital of Zhengzhou University,Zhengzhou,450000)

机构地区：[1]郑州大学第一附属医院,450000

出　　处：《实用癌症杂志》2024年第8期1373-1376,共4页The Practical Journal of Cancer

摘　　要：目的探讨后腹腔镜辅助小切口保留肾单位手术治疗肾癌患者的疗效及术后复发危险因素。方法选取89例肾癌患者,根据术式差异分为2组。研究组患者40例,采用后腹腔镜辅助下小切口保留肾单位手术治疗,而对照组患者49例,则采用传统的后腹腔镜下根治性肾切除术治疗。比较2组患者的临床疗效等差异。随访2年,统计术后复发情况并分析其影响因素。结果研究组的术中出血量、术后引流量等指标均优于对照组,但研究组的手术时间较对照组长(P<0.05)。术前2组的肾功能指标比较无差异(P>0.05),而术后2组的肾功能指标均较术前有所改善,且研究组更优(P<0.05)。术后研究组的并发症发生率(7.5%)显著低于对照组(24.4%)(P<0.05)。年龄≥65岁、血尿、吸烟、淋巴结转移均为肾癌患者术后复发的危险因素(P<0.05)。结论后腹腔镜辅助小切口保留肾单位手术对肾癌患者的疗效较佳,同时还可显著改善患者的肾功能并降低术后并发症发生率,且对肾癌术后复发无影响,值得临床推广应用。Objective To evaluate the efficacy of laparoscopic-assisted minimally invasive nephron-sparing surgery in treating renal cancer patients and identify postoperative recurrence risk factors.Methods A total of 89 renal cancer patients were selected and divided into 2 groups based on the surgical approach.In the study group,40 patients underwent laparoscopic-assisted minimally invasive nephron-sparing surgery,while in the control group,49 patients underwent traditional laparoscopic radical nephrectomy.The clinical outcomes of the 2 groups were compared.Followed up for 2 years,postoperative recurrence and influence factors were analyzed.Results The study group showed better intraoperative blood loss,postoperative drainage,and other indicators compared to the control group,but the duration of surgery was longer in the study group(P<0.05).There were no significant differences in preoperative renal function indicators between the 2 groups(P>0.05),but postoperative renal function indicators improved in both groups compared to preoperative levels,with better results in the study group(P<0.05).The incidence of complications in the study group(7.5%)was significantly lower than that in the control group(24.4%)(P<0.05);age≥65 years,hematuria,smoking,and lymph node metastasis were identified as risk factors for postoperative recurrence in renal cancer patients(P<0.05).Conclusion Laparoscopic-assisted minimally invasive nephron-sparing surgery demonstrates superior efficacy in treating renal cancer patients,significantly improves renal function,reduces the incidence of postoperative complications,but has no impact on postoperative recurrence in renal cancer,thus warranting clinical application.

关 键 词：后腹腔镜辅助小切口 保留肾单位 肾癌 疗效 术后复发 危险因素 

分 类 号：R737.11[医药卫生—肿瘤]