液体活检在肺癌早期诊断中的应用研究进展  

Research advances in the application of liquid biopsy in the diagnosis of early-stage lung cancer

作　　者：黄彤彤 辛颖[2] 尹晓娇 孙彦秋 徐涛[1] HUANG Tongtong;XIN Ying;YIN Xiaojiao;SUN Yanqiu;XU Tao(Department of Respiratory and Critical Care Medicine,The Affiliated Hospital of Qing-dao University,Qingdao 266000,China)

机构地区：[1]青岛大学附属医院呼吸与危重症医学科,山东青岛266000 [2]青岛大学附属医院内分泌与代谢性疾病科,山东青岛266000

出　　处：《青岛大学学报（医学版）》2024年第3期470-474,共5页Journal of Qingdao University(Medical Sciences)

基　　金：山东省医药卫生科技发展计划项目(2018WS379)。

摘　　要：液体活检是肺癌诊断的一种重要方法,较之传统组织活检,有安全无创、标本易获取、可动态监测等优势,在早期肺癌诊断中有确切价值。本文总结国内外液体活检诊断早期肺癌的研究进展,探讨其在早期肺癌诊断中的价值。Liquid biopsy is an important method for the diagnosis of lung cancer,and compared with traditional tissue biopsy,liquid biopsy has the advantages of favorable safety,noninvasiveness,convenience in obtaining specimens,and dynamic monitoring.Therefore,it has a marked value in the diagnosis of early-stage lung cancer.This article summarizes the research advances in liquid biopsy in the diagnosis of early-stage lung cancer in China and globally and discusses its value in the diagnosis of early-stage lung cancer.

关 键 词：液体活组织检查 肺肿瘤 早期诊断 生物标记 肿瘤 综述 

分 类 号：R734.2[医药卫生—肿瘤] R446.8[医药卫生—临床医学]