免疫学指标在感染性与非感染性葡萄膜炎患者中的鉴别诊断价值  

Differential Diagnosis Value of Immunological Indexes on Patients with Infectious and Non-infectious Uveitis

作　　者：王玮 邓文 毛文义 唐小鹃 李丽萍 WANG Wei;DENG Wen;MAO Wenyi;TANG Xiaojuan;LI Liping(Department of Laboratory,the Second People's Hospital of Jingdezhen,Jingdezhen 333000,China;不详)

机构地区：[1]景德镇市第二人民医院(景德镇市细胞与分子重点实验室)检验科,江西景德镇333000 [2]江西鄱阳湖医院检验科,江西鄱阳333100 [3]景德镇市第二人民医院眼科,江西景德镇333000

出　　处：《中国医学创新》2024年第22期115-119,共5页Medical Innovation of China

基　　金：景德镇市科技计划项目(20231SFZC066)。

摘　　要：目的:分析免疫学指标在感染性与非感染性葡萄膜炎患者中的鉴别诊断价值。方法:回顾性分析2022年1月—2023年10月景德镇市第二人民医院收治的100例不明病因的葡萄膜炎患者资料。比较感染性与非感染性葡萄膜炎基线资料、常规生化检验结果,以最终综合诊断为标准,分析免疫学指标对感染性与非感染性葡萄膜炎的鉴别诊断效能。结果:100例不明病因的葡萄膜炎患者,最终诊断感染性葡萄膜炎32例/55眼(感染组),非感染性葡萄膜炎68例/114眼(非感染组)。感染组病因占比最高为急性视网膜坏死综合征(50.00%),最低为梅毒葡萄膜炎(6.25%);非感染组病因占比最高为特发性葡萄膜炎(51.47%),最低为Fuchs综合征(2.94%);两组基线资料、常规生化检验结果差异均无统计学意义(P>0.05)。免疫学指标对感染性与非感染性葡萄膜炎的检出率分别为87.50%、92.65%,与综合诊断比较差异均无统计学意义(P>0.05)。结论:免疫学指标在感染性与非感染性葡萄膜炎患者中的存在较高鉴别诊断价值。Objective:To analyze the value of immunological indexes in the differential diagnosis of patients with infectious and non-infectious uveitis.Method:The data of 100 patients with uveitis of unknown etiology admitted to the Second People's Hospital of Jingdezhen were reviewed from January 2022 to October 2023.The baseline data and routine biochemical test results of patients with infectious and non-infectious uveitis were compared,and the efficacy of immunological indexes in the differential diagnosis of infectious and non-infectious uveitis was analyzed.Result:Of 100 patients with uveitis of unknown etiology,the final diagnosis included infectious uveitis in 32 cases/55 eyes(infection group)and non-infectious uveitis in 68 cases/114 eyes(non-infection group).In the infection group,the highest cause was acute retinal necrosis syndrome(50.00%)and the lowest was syphilis uveitis(6.25%).In the non-infection group,the highest cause was idiopathic uveitis(51.47%)and the lowest was Fuchs syndrome(2.94%).There were no statistical differences in the results of baseline data and routine biochemical tests between the two groups(P>0.05).The detection rates of immunological indexes for infectious uveitis and noninfectious uveitis were 87.50%and 92.65%respectively,which were not statistically different from comprehensive diagnosis(P>0.05).Conclusion:Immunological indexes have high differential diagnosis value on patients with infectious and non-infectious uveitis.

关 键 词：免疫学诊断 感染性葡萄膜炎 非感染性葡萄膜炎 鉴别诊断 

分 类 号：R773.9[医药卫生—眼科]