实时超声引导微波消融术与腹腔镜病灶 切除术在子宫腺肌瘤患者中的应用效果  

Application Effect of Real-time Ultrasound-guided Microwave Ablation and Laparoscopic Lesion Resection in Patients with Uterine Adenomyoma

作　　者：刘慧 张桂华 LIU Hui;ZHANG Guihua(Department of Gynaecology,Liaocheng Infectious Disease Hospital,Liaocheng 252000,China;不详)

机构地区：[1]聊城市传染病医院妇科,山东聊城252000

出　　处：《中国医学创新》2024年第20期52-56,共5页Medical Innovation of China

摘　　要：目的:探究实时超声引导微波消融术与腹腔镜病灶切除术在子宫腺肌瘤患者中的应用效果。方法:选择2021年1月—2023年1月在聊城市传染病医院治疗的子宫腺肌瘤患者80例,应用随机数字表法将其分为对照组(行腹腔镜病灶切除术)及观察组(行实时超声引导微波消融术),各40例。对比两组临床指标、子宫体积、月经量[月经失血图(PBAC)]、痛经评分[视觉模拟评分法(VAS)]、卵泡刺激素(FSH)、雌二醇(E_(2))、黄体生成素(LH)、糖类抗原125(CA125)、糖类抗原19-9(CA19-9)、并发症发生情况。结果:观察组术中出血量少于对照组,手术时间、住院时间均短于对照组,差异均有统计学意义(P<0.05)。术后,两组子宫体积均缩小,PBAC、VAS评分均降低,观察组子宫体积小于对照组,PBAC、VAS评分均低于对照组,差异均有统计学意义(P<0.05)。术后,两组FSH、E_(2)、LH水平比较,差异均无统计学意义(P>0.05)。术后,两组CA125、CA19-9均降低,观察组CA125、CA19-9均低于对照组,差异均有统计学意义(P<0.05)。对照组并发症发生率高于观察组,差异有统计学意义(P<0.05)。结论:子宫腺肌瘤行实时超声引导微波消融术治疗,可缩小子宫体积,减少月经量,缓解痛经,降低CA125、CA19-9水平,安全性较高。Objective:To explore the application effect of real-time ultrasound-guided microwave ablation and laparoscopic lesion resection in patients with uterine adenomyoma.Method:A total of 80 patients with uterine adenomyoma treated in Liaocheng Infectious Disease Hospital from January 2021 to January 2023 were selected and divided into control group(underwent laparoscopic lesion resection)and observation group(underwent real-time ultrasound-guided microwave ablation)by random number table method,with 40 cases in each group.Clinical indicators,uterine volume,menstrual volume[pictorial blood loss assessment chart(PBAC)],dysmenorrhea score[visual analogue scale(VAS)],follicle stimulating hormone(FSH),estradiol(E_(2)),luteinizing hormone(LH),carcinoembryonic antigen(CA125),carbohydrate antigen 19-9(CA19-9)and complications were compared between the two groups.Result:The intraoperative bleeding volume in the observation group was less than that in the control group,and the operation time and hospital stay were shorter than those in the control group,the differences were statistically significant(P<0.05).After operation,uterine volume were reduced in both groups,PBAC and VAS scores were decreased,and the uterine volume of observation group was smaller than that of control group,PBAC and VAS scores were lower than those of control group,the differences were statistically significant(P<0.05).After operation,there were no significant differences in FSH,E_(2) and LH levels between the two groups(P>0.05).After operation,CA125 and CA19-9 were decreased in both groups,and CA125 and CA19-9 in observation group were lower than those in control group,the differences were statistically significant(P<0.05).The incidence of complications in control group was higher than that in observation group,the difference was statistically significant(P<0.05).Conclusion:Real-time ultrasound-guided microwave ablation for uterine adenomyoma can reduce uterine volume,reduce menstrual volume,relieve dysmenorrhea,and reduce CA125 and CA19-9 levels,with h

关 键 词：实时超声引导微波消融术 腹腔镜病灶切除术 子宫腺肌瘤 安全性 

分 类 号：R737.33[医药卫生—肿瘤]