应用异体硬脑膜行改良后巩膜加固术治疗病理性近视的临床效果观察  

Clinical Observation of the Effect of Modified Posterior Sclera Reinforcement Using Allogeneic Dura Meninge in the Treatment of Pathological Myopia

作　　者：兰丽霞[1] 利佩茜 叶波[1] 邱新文[1] 任旋[1] LAN Lixia;LI Peiqian;YE Bo;QIU Xinwen;REN Xuan(Department of Fundus,Nanchang Aier Eye Hospital,Nanchang 330000,China;不详)

机构地区：[1]南昌爱尔眼科医院眼底科,江西南昌330000

出　　处：《中国医学创新》2024年第20期133-136,共4页Medical Innovation of China

基　　金：江西省卫生健康委科技计划项目(202311352)。

摘　　要：目的:探讨应用异体硬脑膜行改良后巩膜加固术(PSR)治疗病理性近视(PM)的临床效果。方法:选择2022年1—10月南昌爱尔眼科医院收治30例(33只眼)PM患者,均应用异体硬脑膜行改良PSR治疗。比较治疗前后屈光度(SE)、眼轴长度、视盘与黄斑血流密度、最佳矫正视力(BCVA)、眼压(IOP),并记录术后并发症发生情况。结果:治疗后3个月,SE及黄斑区浅层毛细血管丛(SCP)、深层毛细血管丛(DCP)血流密度均高于治疗前,眼轴长度短于治疗前,差异均有统计学意义(P<0.05)。治疗前、治疗后3个月,BCVA、IOP、视盘内及周围血流密度比较,差异均无统计学意义(P>0.05)。术后短期内30例患者未发生严重并发症,但均出现轻度结膜充血水肿,症状2周后明显缓解,有3例(3只眼)出现轻度视物变形,4例(4只眼)出现一过性眼压升高,使用7 d降眼压滴眼液后均改善。结论:应用异体硬脑膜行改良PSR治疗PM安全可行,改善黄斑区视网膜血流循环,延缓SE、眼轴长度增长。Objective:To investigate the clinical effect modified posterior scleral reinforcement(PSR)using allogeneic dura meninge in the treatment of pathologic myopia(PM).Method:A total of 30 patients(33 eyes)with PM admitted to Nanchang Aier Eye Hospital from January to October 2022 were selected,and all of them were treated with modified PSR using allogeneic dura meninge.The diopter(SE),ocular axis length,blood flow density of optic disc and macular,best corrected visual acuity(BCVA)and intraocular pressure(IOP)were compared before and after treatment,and the postoperative complications were recorded.Result:At 3 months after treatment,the SE,blood density of superficial capillary plexus(SCP),deep capillary plexus(DCP)in macular area was higher than those before treatment,and ocular axis length was shorter than that before treatment,the differences were statistically significant(P<0.05).There were no significant differences in BCVA,IOP,blood density in and around optic disc before treatment and 3 months after treatment(P>0.05).No serious complications occurred in 30 patients in the short term after surgery,but all of them developed mild conjunctival hyperemia and edema,symptoms were significantly relieved after 2 weeks,3 cases(3 eyes)had mild visual deformation,and 4 cases(4 eyes)had transient intraocular pressure increase,all of which improved after 7 d of intraocular pressure lowering drops.Conclusion:Modified PSR using allogeneic dura meninge is safe and feasible to treat PM,improve retinal blood circulation in macular area,and delay the growth of SE and ocular axis length.

关 键 词：病理性近视 异体硬脑膜 改良后巩膜加固术 眼轴长度 屈光度 黄斑血流密度 

分 类 号：R779.6[医药卫生—眼科]