贝类线粒体双单亲遗传研究进展  

Research advances in mitochondrial doubly uniparental inheritance in bivalves

作　　者：许然 胡梦阳 丁淑荃[1] 李西雷[1] 张云龙[1] XU Ran;HU Mengyang;DING Shuquan;LI Xilei;ZHANG Yunlong(College of Animal Science and Technology,Anhui Agricultural University,Hefei 230036,China)

机构地区：[1]安徽农业大学动物科技学院,安徽合肥230036

出　　处：《海洋科学》2024年第5期107-115,共9页Marine Sciences

基　　金：国家自然科学基金青年科学基金项目(23239040)。

摘　　要：真核生物经历了多次独立演化来保证细胞器的母系遗传模式,然而一些双壳贝类却演化出了一套稳定的可随父、母本传递的独特线粒体遗传模式——双单亲遗传。在双单亲遗传贝类中同时存在两种遗传差异极大的线粒体基因组(F型和M型),可以分别随父本和母本传递给后代。贝类双单亲遗传自首次发现至今已有30多年,目前其遗传调控机制仍不清楚,本文回顾了独特的双单亲遗传系统及当前研究进展,并展望其可能应用。贝类双单亲遗传的独特性使其成为研究线粒体遗传与进化、核质冲突、性别分化和发育的极佳材料。Eukaryotes have undergone numerous instances of independent evolution to ensure the maternal inheritance pattern of organelles.However,certain bivalves have evolved a unique mitochondrial inheritance system known as doubly uniparental inheritance,in which maternal and paternal mitochondrial DNA(F-and M-types,respectively)are passed on to offspring.Although the doubly uniparental inheritance pattern was first identified in bivalves over 30 years ago,the genetic mechanisms governing it remain largely enigmatic.This article reviews the doubly uniparental inheritance system,summarizing the current state of research and exploring potential future applications.The uniqueness of this system in bivalves presents an invaluable resource for studies on mitochondrial inheritance and evolution,mito-nuclear conflict,and sex determination.

关 键 词：贝类双单亲遗传 线粒体与核共调控 性别遗传 氧化磷酸化 

分 类 号：S917.4[农业科学—水产科学]