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作 者:Yasir M Khayyat
机构地区:[1]Department of Medicine,Faculty of Medicine,Umm AL-Qura University,Makkah 8156-24381,Saudi Arabia
出 处:《World Journal of Clinical Cases》2024年第27期6007-6010,共4页世界临床病例杂志
摘 要:Upper gastrointestinal bleeding(UGIB)can be attributed to either non-variceal or variceal causes.The latter is more aggressive with hemodynamic instability secondary to decompensated cirrhosis and portal hypertension.Non-variceal UGIB(NVUGIB)occurs due to impaired gastroprotective mechanisms attributed to several drugs such as anticoagulants and nonsteroidal anti-inflammatory drugs.Helicobacter pylori infection contributes to the development of peptic ulcer bleeding as well.NVUGIB presentation can be either hemodynamically stable or unstable.During the initial assessment a scoring system including patient-related factors(current cardiac,renal,and liver diseases and hemodynamic and labo-ratory parameters)is used to determine the patient’s prognosis.The Glasgow Blatchford score has been shown to be the most useful and precise.Those with high-risk NVUGIB require urgent assessment and upper endoscopy to achieve better short-term and long-term outcomes such as less hospitalization,blood transfusion,and surgery.
关 键 词:GASTRIC PEPTIC Non-steroidal anti-inflammatory drugs ANTICOAGULANTS MELENA
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