Interferon-gamma release assays as a tool for differential diagnosis of gastrointestinal tuberculosis  

作　　者：Tsvetelina Velikova Anita Aleksandrova 

机构地区：[1]Medical Faculty,Sofia University Street Kliment Ohridski,Sofia 1407,Bulgaria [2]Department of Immunology,Medical-diagnostic laboratory Ramus,Simitli 6000,Bulgaria

出　　处：《World Journal of Clinical Cases》2024年第27期6015-6019,共5页世界临床病例杂志

基　　金：The European Union-Next Generation EU,through the National Recovery and Resilience Plan of the Republic of Bulgaria,Project,No.BG-RRP-2.004-0008.

摘　　要：In this editorial,we comment on an article published in a recent issue of the World Journal of Clinical Cases.There is a pressing need for reliable tools for diagnosing tuberculosis(TB)of the gastrointestinal tract.Despite advancements in the diagnosis and treatment,TB remains a global health challenge.Ali et al demon-strated that TB may mimic gastrointestinal conditions,such as gastric outlet obstruction,causing a delay in the diagnosis.Furthermore,the latter complication is frequently observed during infections,including Helicobacter pylori,and rarely is related to TB,as in the presented case.In line with this,we think that laboratory tests based on interferon-gamma release assays can be a helpful tool for diagnosing latent TB paced in the gastrointestinal tract.Innovative strategies and approaches for diagnosing latent/active extra pulmonary TB are crucial for establishing the diagnosis early and enhancing treatment strategies to mitigate the global burden of TB.

关 键 词：TUBERCULOSIS Gastrointestinal tuberculosis Interferon-gamma release assay IGRA Primary gastroduodenal tuberculosis Gastric outlet obstruction Case report 

分 类 号：R57[医药卫生—消化系统] R446[医药卫生—内科学]