Incidental renal cell carcinoma post bilateral nephrectomy in autosomal dominant polycystic kidney disease  

作　　者：Min-Ho Shin Nam-Kyu Choi 

机构地区：[1]Division of General Surgery,Department of Hepato-Bilio-Pancreatic Surgery and Transplantation Surgery,Chosun University College of Medicine,Gwangju 61453,South Korea

出　　处：《World Journal of Clinical Cases》2024年第28期6187-6194,共8页世界临床病例杂志

基　　金：The Research fund from the Chosun University Hospital,No.2023-26.

摘　　要：BACKGROUND Renal cell carcinoma(RCC)is more common in patients with autosomal dominant polycystic kidney disease(ADPKD)than in the general population.Diagnosing RCC in ADPKD is challenging due to the presence of multiple renal cysts,often leading to delays and difficulties in distinguishing RCC from cyst infection or hemorrhage.A total of 38 kidneys were excised from 19 patients,with a mean age of 56.8 years and an average hemodialysis duration of 84.2 months.Eight patients underwent open nephrectomies,and 11 underwent hand-assisted laparoscopic nephrec-tomies.RCC was detected in 15.8%of kidneys,affecting 21.1%of patients.Two patients had multifocal RCC in both kidneys.All RCC cases were pT1 stage,with the largest lesion averaging 16.5 mm in diameter.The average operative duration was 120 minutes,with intraoperative blood loss averaging 184.2 mL.Five patients required blood transfusions.Postoperative complications occurred in five patients,with a mean hospital stay of 17.1 days.The mean follow-up period was 28.1 months.CONCLUSION The prevalence of RCC is higher in patients with ADPKD with ESRD than in those with ESRD alone.Thus,clinicians should be cautious and implement surveillance programs to monitor the development of RCC in patients with ADPKD,particularly those on dialysis.

关 键 词：Renal cell carcinoma Autosomal dominant polycystic kidney disease End-stage renal disease Kidney transplantation NEPHRECTOMY 

分 类 号：R737.11[医药卫生—肿瘤]