Unveiling hidden outcomes in malignant gastric outlet obstruction research–insights from a"Pancreas 2000"review  

作　　者：Filipe Vilas-Boas Giacomo Emanuele Maria Rizzo Charles De Ponthaud Stuart Robinson Sebastien Gaujoux Gabriele Capurso Giuseppe Vanella Bahadır Bozkırlı 

机构地区：[1]Department of Gastroenterology,São João University Hospital,Porto 4200,Portugal [2]Endoscopy Service,Department of Diagnostic and Therapeutic Services,Scientific Institute for Research,Hospitalization and Healthcare-The Mediterranean Institute for Transplantation and Highly Specialized Therapies,Palermo 90127,Sicilia,Italy [3]Department of Digestive,Hepato-Biliary and Pancreatic Surgery and Liver Transplantation,AP-HP Pitié-Salpêtriere,Sorbonne Université,Paris 75013,Île-de-France,France [4]Department of Hepatobiliary,Pancreatic and Transplant Surgery,Freeman Hospital,Newcastle NE77DN,Newcastle upon Tyne,United Kingdom [5]Division of Pancreato-Biliary Endoscopy and Endosonography,Pancreas Translational and Clinical Research Center,IRCCS San Raffaele Scientific Institute,Vita-Salute San Raffaele University,Milano 20132,Italy [6]Department of General Surgery,HPB-Unit,Acıbadem Maslak Hospital,Istanbul 34398,Türkiye

出　　处：《World Journal of Gastrointestinal Endoscopy》2024年第8期451-461,共11页世界胃肠内镜杂志（英文版）（电子版）

摘　　要：Malignant gastric outlet obstruction(mGOO)is a major condition affecting patients with periampullary tumors,including pancreatic cancer.The current treatment options include surgical gastroenterostomy,endoscopic stenting and more recently EUS-guided gastroenterostomy.Most studies comparing the outcomes of the three procedures focus on technical success,clinical success and safety.Several“occult”outcomes relevant to the patient’s viewpoints and perspective may ultimately impact on cancer-related and overall survival,such as body mass composition,nutritional biomarkers,chemotherapy tolerance and patient-reported quality of life.The aim of this review is to provide an overview of potential key outcomes that should be explored in future comparative research around mGOO treatment options.

关 键 词：Malignant gastric outlet obstruction Endoscopic ultrasound-guided gastroenterostomy Patient-reported outcomes Body composition NUTRITION Quality of life 

分 类 号：R57[医药卫生—消化系统]