2010-2019年甘肃省肿瘤登记地区肺癌死亡特征及疾病负担分析  

Analysis on the death characteristics and disease burden of lung cancer in Gansu cancer registration areas from 2010 to 2019

作　　者：鲁朝霞 马菊红[1] 马骥雄[1] 周红[1] 薛娟娟 丁高恒 刘玉琴[2] 王引弟 吕珍 LU Zhaoxia;MA Juhong;MA Jixiong;ZHOU Hong;XUE Juanjuan;DING Gaoheng;LIU Yuqin;WANG Yindi;LYU Zhen(Department of Chronic Non-communicable Disease Prevention and Control,Baiyin Center for Disease Control and Prevention,Baiyin,Gansu Province 730900,China;不详)

机构地区：[1]白银市疾病预防控制中心慢性非传染性疾病预防控制科,甘肃省白银730900 [2]甘肃省肿瘤医院癌症防治办公室,甘肃省兰州730050 [3]甘肃中医药大学公共卫生学院,甘肃省兰州730050

出　　处：《中国慢性病预防与控制》2024年第6期434-439,444,共7页Chinese Journal of Prevention and Control of Chronic Diseases

基　　金：白银市2023年第一批科技计划项目(2023-1-51Y);兰州市科技指导项目(2019-ZD-133)。

摘　　要：目的 了解2010-2019年甘肃省肿瘤登记地区肺癌死亡水平变化趋势及疾病负担情况,为甘肃省肺癌防控提供参考。方法 数据来源于甘肃省肿瘤登记地区2010-2019年的肺癌死亡登记数据,用SPSS 27.0软件计算死亡率及疾病负担等相关指标,采用Joinpoint 5.2软件进行率的变化趋势分析,计算年度变化百分比(APC)。结果 2010-2019年甘肃省肿瘤登记地区肺癌死亡率为23.71/10万,中标死亡率、世标死亡率分别为22.45/10万、18.02/10万,0~74岁累积率为2.19%,35~64岁截缩率为23.33/10万。男性肺癌死亡率(31.21/10万)高于女性(15.81/10万),差异均有统计学意义(P<0.05)。2010-2019年肺癌死亡率呈上升趋势,变化趋势有统计学意义(APC=7.97%,P<0.05)。肺癌死亡率在0~<45岁年龄组均处于较低水平,45岁之后随着年龄增长死亡率快速上升,男性、城市地区、农村地区人群均在80~84岁组达到死亡高峰,女性人群在85岁及以上年龄组达到死亡高峰;65岁及以上人群肺癌死亡率在2010-2019年呈上升趋势,变化趋势有统计学意义(APC=5.66%,P<0.05)。2010-2019年甘肃省肺癌所致人群潜在减寿年数为41 847人年,标化潜在减寿年数为39 138人年,平均潜在减寿年数为11.34年,潜在减寿率为1.55‰,标化潜在减寿年数率为1.45‰;肺癌所致潜在工作损失年数为39 025人年,标化潜在工作损失年数为36 746人年,平均潜在工作损失年数为14.56年,潜在工作损失率为1.41‰,标化潜在工作损失率为1.33‰。结论 甘肃省肿瘤登记地区肺癌疾病负担较重,应开展针对性健康教育和肺癌筛查,有效降低肺癌死亡率与疾病负担。Objective To understand the death level trend and disease burden of lung cancer in Gansu cancer registration areas from 2010 to 2019,and provide the reference for lung cancer prevention and control in Gansu Province.Methods Data were from the lung cancer death registration data in the cancer registration areas of Gansu Province from 2010 to 2019.The mortality rates and disease burden were calculated using SPSS 27.0 software.Joinpoint 5.2 software was used to analyze the change trend of rate,and to calculate the annual percentage change(APC).Results The lung cancer mortality rate in the cancer registration areas of Gansu Province from 2010 to 2019 was 23.71/10^(5),the standardized mortality rates was 22.45/10^(5) and 18.02/105 according to the Chinese population and the world standard population,respectively.The cumulative rate in the 0-74 age group was 2.19%,and the age-adjusted truncated rate in the 35-64 age group was 23.33/10^(5).The mortality rate(31.21/105)of males was significantly higher than that(15.81/105)of females(P<0.05).The lung cancer mortality rate showed an increasing trend from 2010 to 2019(APC=7.97%,P<0.05).The mortality rate for lung cancer remained relatively low level in the 0-<45 years old group,but increased rapidly in the≥45 years old group.Male,urban and rural areas all reached peak mortality between 80-84 years old,the female population reached the mortality peak in≥85 years old group.The mortality rate for lung cancer in the≥65 years old group showed a significantly increasing trend from 2010 to 2019(APC=5.66%,P<0.05).The potential years of life lost(PYLL)due to lung cancer in Gansu Province from 2010 to 2019 were 41847 person-years,the standardized PYLL was 39138 person-years.The average PYLL was 11.34 years,and the PYLL rate was 1.55‰,the standardized PYLL rate was 1.45‰.The potential years of work lost(WPYLL)due to lung cancer were 39025 person-years,the standardized WPYLL were 36746 person-years.The average WPYLL was 14.56 years,and the WPYLL rate was 1.41‰,the standardi

关 键 词：肺癌 死亡特征 疾病负担 变化趋势 

分 类 号：R734.2[医药卫生—肿瘤]