2015—2019年四川省肿瘤登记地区甲状腺癌流行特征及趋势分析  

Epidemiologic Characteristics and Trends of Thyroid Cancer in Sichuan Cancer Registration Areas from 2015 to 2019

作　　者：刘清霞[1] 王丹 袁芝佩 陈莉萍 赵璐 邓颖[3] 成姝雯 LIU Qingxia;WANG Dan;YUAN Zhipei;CHEN Liping;ZHAO Lu;DENG Ying;CHENG Shuwen(Yaan Center for Disease Control and Prevention,Yaan 625000,China;Guang’an Center for Disease Control and Prevention,Guang’an 638000,China;Sichuan Center for Disease Control and Prevention,Chengdu 610041,China)

机构地区：[1]雅安市疾病预防控制中心,四川雅安625000 [2]广安市疾病预防控制中心,四川广安638000 [3]四川省疾病预防控制中心,四川成都610041

出　　处：《中国肿瘤》2024年第7期523-528,共6页China Cancer

摘　　要：[目的]分析四川省肿瘤登记地区2015—2019年甲状腺癌发病与死亡情况及变化趋势。[方法]利用四川省各肿瘤登记处上报且质控合格的甲状腺癌发病与死亡资料,分性别、城乡、年龄组计算甲状腺癌发病(死亡)率、标化发病(死亡)率等指标。利用Joinpoint软件计算年度变化百分比(APC),分析2015—2019年变化趋势。[结果]2015—2019年四川省肿瘤登记地区甲状腺癌粗发病率为4.29/10万,中标率为3.63/10万,世标率为3.14/10万;粗死亡率为0.37/10万,中标率为0.22/10万,世标率为0.21/10万。女性发病(死亡)率、标化发病(死亡)率均高于男性,城市地区发病(死亡)率、标化发病(死亡)率均高于农村地区。甲状腺癌发病率在50~54岁组达到最高值,死亡率在85岁及以上年龄组达到最高值。2015—2019年四川省肿瘤登记地区甲状腺癌发病率呈上升趋势(P<0.05),女性、城市地区和农村地区发病率也呈上升趋势(P均<0.05)。全省肿瘤登记地区甲状腺癌死亡率、标化死亡率均维持在较低水平(P>0.05)。不同年龄组甲状腺癌发病率变化趋势不同,30~39岁组上升速度最快(APC=36.90%,P<0.05)。各年龄组甲状腺癌死亡率呈上升趋势,但是趋势变化均无统计学意义(P均>0.05)。[结论]四川省肿瘤登记地区甲状腺癌发病呈快速上升趋势,应通过综合干预措施,减轻甲状腺癌的疾病负担。[Purpose]To analyze the incidence,mortality and trends of thyroid cancer in cancer registration areas of Sichuan from 2015 to 2019.[Methods]The incidence and mortality of thyroid cancer and registered population data of Sichuan Province were collected,the crude incidence/mortality rate,age-standardized rates by Chinese standard population(ASIRC,ASMRC)and world standard population(ASIRW,ASMRW)were calculated.Use the Joinpoint software the annual percentage change(APC)was calculated for analyzing the trends of the incidence and mortality.[Results]The crude incidence rate of thyroid cancer in cancer registration areas of Sichuan from 2015 to 2019 was 4.29/105,with the ASIRC of 3.63/105 and ASIRW of 3.14/105.The crude mortality rate was 0.37/105,with the ASIRC of 0.22/105 and ASIRW of 0.21/105.The incidence and mortality rates for women were higher than those for men.The incidence and mortality rates for urban areas were higher than those for rural areas.The incidence reached the highest in the age group of 50~54 years old.The mortality reached the highest in the age group of 85+years old.The incidence was increased in cancer registration areas of Sichuan from 2015 to 2019(P<0.05),while the mortality rate remained at a lower level(P>0.05).The incidence of thyroid cancer increased rapidly from 2015 to 2019 in the age group of 30~39 years old(APC=36.90%,P<0.05).The increase of mortality rate of thyroid cancer from 2015 to 2019 was not statistically significant(P>0.05).[Conclusion]The incidence of thyroid cancer in cancer registration areas of Sichuan Province is on the rise rapidly.Comprehensive interventions should be carried out to reduce the disease burden of thyroid cancer.

关 键 词：甲状腺癌 发病率 死亡率 趋势 四川 

分 类 号：R73-31[医药卫生—肿瘤] R736.1[医药卫生—临床医学]