SNHG1在肿瘤中的研究进展  

Research progress of SNHG1 in tumor

作　　者：孔妮 马红[2] 罗洞波[1] KONG Ni;MA Hong;LUO Dongbo(The Second Department of Thoracic Surgery,Affiliated Tumor Hospital of Xinjiang Medical University,Xinjiang Uygur Autonomous Region,Urumqi830011,China;School of Basic Medical Sciences,Xinjiang Medical University,Urumqi830017,China)

机构地区：[1]新疆医科大学附属肿瘤医院胸外二科,新疆乌鲁木齐830011 [2]新疆医科大学基础医学院,新疆乌鲁木齐830017

出　　处：《中国医药导报》2024年第19期51-55,61,共6页China Medical Herald

基　　金：省部共建中亚高发病成因与防治国家重点实验室开放课题基金项目(SKL-HIDCA-2022-17)。

摘　　要：SNHG1在多种癌症中异常表达,且作为肿瘤驱动因子参与细胞的增殖、周期、凋亡、迁移和侵袭等多个过程的调控。SNHG1有潜力成为肿瘤诊断、治疗和预后评估的新生物标志物和治疗靶点。本文综述SNHG1的发病机制及其在肿瘤发生、发展中作用的最新研究进展,以期为肿瘤的早期诊断和早期治疗提供新的依据和方向。SNHG1 is aberrantly expressed in a variety of cancers and participates as a tumor driver in the regulation of multiple processes such as cell proliferation,cycling,apoptosis,migration,and invasion,etc.SNHG1 has potential to become a new biomarker and therapeutic target for tumor diagnosis,treatment,and prognostic assessment.This article reviews latest research progress on the pathogenesis of SNHG1 and the role of SNHG1 in tumor genesis and development,with a view to providing a new basis and direction for early diagnosis and early treatment of tumors.

关 键 词：肿瘤 SNHG1 长链非编码RNA 研究进展 

分 类 号：R73[医药卫生—肿瘤]