边缘区淋巴瘤临床诊疗路径  

Clinical pathway for the diagnosis and treatment of marginal zone lymphoma

作　　者：中西南惰性淋巴瘤联盟 向茜茜 颜文哲 崔国惠[4] 胡豫[5] 吕奔 张曦 彭宏凌[6] Indolent Lymphoma Alliance of Central and Southwest China(ILACSC)

机构地区：[1]不详 [2]陆军军医大学第二附属医院血液病医学中心,重庆400037 [3]中南大学湘雅二医院血液内科,长沙410011 [4]华中科技大学同济医学院附属协和医院血液科,武汉430022 [5]华中科技大学同济医学院附属协和医院,武汉430022 [6]中南大学湘雅二医院血液内科,长沙41001l

出　　处：《临床血液学杂志》2024年第7期437-445,共9页Journal of Clinical Hematology

摘　　要：边缘区淋巴瘤(MZL)是一种常见的惰性淋巴瘤,其特点是临床症状复杂多样、病理缺乏特异性、异质性较强、临床诊断困难、治疗选择差异性大。为进一步推动MZL的规范化诊疗,中西南惰性淋巴瘤专家团队参照国内外指南/共识并结合我国临床实践,撰写并推出了本部临床诊疗路径,从三种主要亚型MZL的临床表现、检验检查、诊断及鉴别诊断、分期及预后以及分层治疗等方面进行了详细的阐述,特别是以路线图的形式直观地为各亚型MZL给出了规范化诊疗流程推荐,方便临床一线和基层医务人员参考,共同提高我国MZL的诊疗水平。Marginal zone lymphoma(MZL)is a common indolent lymphoma characterized by complex and diverse clinical symptoms,non-specific pathology,strong heterogeneity,difficult clinical diagnosis,and significant variation in treatment options.To further promote the standardized diagnosis and treatment of MZL,an expert team specializing in indolent lymphoma from central and southwest China,referencing both domestic and international guidelines/consensuses and integrating them with clinical practice in China,has developed and released this clinical diagnosis and treatment pathway.This document provides a detailed elaboration on the clinical manifestations,laboratory tests,diagnosis and differential diagnosis,staging and prognosis,and stratified treatment of the three main subtypes of MZL.Notably,it offers a standardized diagnostic and treatment process recommendation for each subtype in an intuitive roadmap format,facilitating reference for frontline and primary care medical personnel,thereby collectively enhancing the level of MZL diagnosis and treatment in China.

关 键 词：边缘区淋巴瘤 分型 诊断 治疗 临床路径 

分 类 号：R733.4[医药卫生—肿瘤]