运脾滋阴法-肠润方治疗脾虚气弱型慢传输型便秘的临床疗效  

Clinical efficacy of the method of nourishing spleen and nourishing yin combined with Chang Run Fang in the treatment of slow transit constipation patients with spleen deficiency and weak qi

作　　者：魏晓玲 洪燕秋 肖秋平[1,2] 林金荣 WEI Xiao-Ling;HONG Yang-Qiu;XIAO Qiu-Ping(Xiamen Hospital of Traditional Chinese Medicine,Fujian University of Traditional Chinese Medicine,Xiamen 361009,Fujian,China)

机构地区：[1]福建中医药大学附属厦门中医院,福建厦门361009 [2]厦门市盆底动力学重点实验室

出　　处：《吉林医学》2024年第8期1895-1899,共5页Jilin Medical Journal

基　　金：国家自然科学基金青年科学基金项目[项目编号:82305255];厦门市科技局卫生项目[项目编号:3502Z20209131];福建中医药大学校管课题[项目编号:XB2021108]。

摘　　要：目的:观察滋阴运脾法-肠润方治疗脾虚气弱型慢传输型便秘(STC)患者的临床疗效。方法:选取60例脾虚气弱型STC患者为研究对象,随机分为对照组和观察组各30例,最终纳入研究对照组27例,观察组28例。观察组口服滋阴运脾法-肠润方,1剂/d。对照组口服乳果糖口服液30 ml/次,1次/d。两组疗程均为4周。比较、分析两组治疗前后患者完全自发排便次数(CSBMs)、便秘主要症状评分、中医证候积分及总有效率。结果:观察组总有效率显著高于对照组,差异有统计学意义(P<0.01);治疗后观察组每周CSBMs较对照组升高,便秘主要症状总分较对照组降低,差异有统计学意义(P<0.01);治疗后观察组在排便频率、排便时间、不尽坠胀感、腹胀的评分及中医证候总分均较对照组降低,差异有统计学意义(P<0.05)。结论:滋阴运脾法-肠润方能有效改善STC脾虚气弱证患者的CSBMs、便秘主要症状及脾虚气弱证候,且对CSBMs、便秘主要症状中排便频率、排便时间、不尽坠胀感、腹胀的改善及中医证候中便次减少、便意减少、腹胀满闷、食少纳呆、神疲懒言、便后乏力的改善优于对照组。Objective To observe the clinical efficacy of the Ziyin Yunpi Method-Changrun Formula in treating slow transit constipation patients with spleen deficiency and weak qi.Method Sixty patients with slow transit constipation due to spleen deficiency and weak qi were selected as research object and randomly divided into a control group and an observation group,with 30 cases in each group.Finally,27 cases were included in the control group and 28 cases were included in the observation group.The observation group takes orally the method of nourishing yin and promoting spleen-Changrun Formula,one dose per day.The control group received oral lactulose oral solution 30 ml/time,once a day.Both groups had a treatment period of 4 weeks.Record the number of complete spontaneous bowel movements(CSBMs),major symptom scores for constipation,and TCM syndrome scores before and after treatment.Results The total effective rate of the observation group was significantly higher than that of the control group,with a statistically significant difference(P<0.01).After treatment,the weekly CSBMs in the observation group increased compared to the control group,and the total score of the main symptoms of constipation in the observation group decreased compared to the control group(P<0.01);After treatment,the observation group showed a decrease in the scores of defecation frequency,defecation time,incomplete bloating,abdominal distension,and the total score of traditional Chinese medicine syndromes compared to the control group(P<0.05).Conclusion The Yin Nourishing and Spleen Nourishing Method-Changrun Formula can effectively improve the CSBMs,main symptoms of constipation,and spleen deficiency and qi deficiency syndrome in patients with slow transit constipation.It is better than the control group in improving CSBMs,main symptoms of constipation,such as defecation frequency,defecation time,incomplete bloating sensation,abdominal distension,and traditional Chinese medicine syndrome,such as reduced bowel frequency,decreased bowel intention,ful

关 键 词：慢传输型便秘 滋阴运脾法-肠润方 脾虚气弱 

分 类 号：R574.62[医药卫生—消化系统]