北京市单中心甲状腺癌患者临床特征的回顾分析  

Retrospective analysis of clinical features of single-center thyroid carcinoma patients in Beijing

作　　者：韩婧 郝少龙 康骅[1] Han Jing;Hao Shaolong;Kang Hua(Department of General Surgery,Xuanwu Hospital,Capital Medical University,Beijing 100053,China;Department of General Surgery,Luhe Hospital,Capital Medical University,Beijing 101149,China)

机构地区：[1]首都医科大学宣武医院普外科,甲状腺乳腺疾病诊疗中心,北京100053 [2]首都医科大学附属北京潞河医院普外科,北京101149

出　　处：《中华普外科手术学杂志（电子版）》2024年第5期490-493,共4页Chinese Journal of Operative Procedures of General Surgery(Electronic Edition)

摘　　要：目的:探讨甲状腺癌患者的主要临床特征及影响因素。方法:回顾分析2014年1月至2018年12月接受手术治疗的1555例甲状腺疾病患者的病例资料,其中甲状腺癌患者867例(55.8%),甲状腺良性疾病患者688例(44.2%)。采用SPSS 19.0软件进行统计学分析。正态分布的计量资料用(x±s)表示,组间比较采用独立样本t检验;计数资料组间比较采用χ^(2)检验;影响因素分析采用Logistic回归分析。P<0.05为差异有统计学意义。结果:4年间甲状腺癌患者收治逐年增加,女性明显多于男性,基本稳定在3~4:1,31~60岁女性应为甲状腺癌重点关注人群。高水平TSH(P<0.001,OR=1.178)与甲状腺癌有相关性。男性(P=0.002,OR=1.599)、较大肿瘤直径(P<0.001,OR=2.364)、高水平TSH(P=0.013,OR=1.215)是甲状腺癌易伴发颈部淋巴结转移的影响因素。结论:高水平TSH与甲状腺癌有相关性。男性、较大肿瘤直径、高水平TSH的甲状腺癌患者易伴发颈部淋巴结转移。Objective:To investigate the main clinical features and influencing factors of thyroid cancer patients.Methods:Data of 1555 patients with thyroid disease who received surgical treatment from January 2014 to December 2018 were retrospectively analyzed,including 867 patients with thyroid cancer(55.8%)and 688 patients with benign thyroid disease(44.2%).SPSS 19.0 software was used for statistical analysis.The measurement data of normal distribution were represented by(x±s),and independent sample t test was used for comparison between groups.χ^(2) test was used to compare the data groups.Logistic regression analysis was used to analyze the influencing factors.P<0.05 was considered statistically significant.Results:In the past 4 years,the treatment of thyroid cancer patients increased year by year,and women were significantly more than men,and basically stabilized at 3-4:1,31-60 years old women should be the focus group of thyroid cancer.High levels of TSH(P<0.001,OR=1.178)were associated with thyroid cancer.Male(P=0.002,OR=1.599),large tumor diameter(P<0.001,OR=2.364),and high TSH level(P=0.013,OR=1.215)were the risk factors for cervical lymph node metastasis of thyroid cancer.Conclusion:High levels of TSH are associated with thyroid cancer.Male thyroid cancer patients with large tumor diameter and high level of TSH are more likely to have cervical lymph node metastasis.

关 键 词：甲状腺肿瘤 甲状腺良性疾病 促甲状腺素 淋巴结转移 影响因素分析 

分 类 号：R736.1[医药卫生—肿瘤]