急性缺血性脑卒中患者不同起病时点NIHSS评分网络分析研究  

Evolution of patterns between NIHSS scores at different onset times in acute ischemic stroke:a network analysis

作　　者：黎冬梅[1] 王伟涛[2] 宋潇宵 古联[2] 彩虹 苏莉[1] LI Dong-mei;WANG Wei-tao;SONG Xiao-xiao;GU Lian;CAI Hong;SU Li(Guangxi Medical University,Nanning,Guangxi 530021,China;不详)

机构地区：[1]广西医科大学,广西南宁530021 [2]广西中医药大学

出　　处：《现代预防医学》2024年第15期2869-2874,共6页Modern Preventive Medicine

基　　金：国家自然科学基金(82160849,81874395);国家中医药传承创新中心项目-优势病种中风及后遗症。

摘　　要：目的通过网络分析探讨急性缺血性脑卒中不同起病时点美国国立卫生研究院卒中量表(NIHSS)评分之间的相互作用模式演变情况。方法收集833例急性缺血性脑卒中患者的NIHSS评分情况,采用网络分析方法对其起病72 h内、起病第7 d的关系进行比较分析。结果在急性缺血性脑卒中患者起病72 h内和起病第7 d NIHSS评分网络分析中,节点强度最强的条目分别为上肢运动(strength=1.48)和意识水平(strength=1.75),边缘权重关联最强的均为上肢运动-下肢运动,边缘权重强度分别为0.63和0.69,节点预测性排在前三位的条目均为上肢运动、下肢运动和意识水平;两个时点的网络相关稳定系数分别为0.75和0.67,两个网络模型没有显著差异(P=0.38)。结论运动功能和意识水平是影响急性缺血性脑卒中患者早期病情的重要因素,其关联关系和预测性在急性期内具有较高的一致性。Objective To investigate the evolving patterns of relationship between NIHSS scores at different onset times in acute ischemic stroke through network analysis.Methods Data on NIHSS scores from 833 patients with acute ischemic stroke were collected.Network analysis methods were used to compare the between NIHSS scores within 72 hours of onset and on day 7.Results In the network analysis of NIHSS scores within 72 hours and on day 7 of onset in patients with acute ischemic stroke,the strongest node strength was observed in upper limb movement(Strength=1.48)and level of cognition(Strength=1.75).The strongest edge weight was both in upper limb movement-lower limb movement(edge weight strength of 0.63 and 0.69).The top three nodes were upper limb movement,lower limb movement,and level of cognition.The network stability for the two time points were 0.75 and 0.67,and there was no significant difference between the two network models(P=0.38).Conclusion Motor function and level of cognition are important factors for the early course of acute ischemic stroke patients,and their correlation and prediction have high consistency in the acute period.

关 键 词：急性缺血性脑卒中 起病时点 NIHSS评分 网络分析 

分 类 号：R743.3[医药卫生—神经病学与精神病学]