发疹性假性血管瘤病14例临床、皮肤镜及组织病理分析  

Clinical,dermatoscopic and histopathological analysis of 14 cases of eruptive pseudoangiomatosis

作　　者：储开宇[1] 王键旋[1] 张怡婷 邵昱伟 罗文峰[1] CHU Kaiyu;WANG Jianxuan;ZHANG Yiting;SHAO Yuwei;LUO Wenfeng(Department of Dermatology,Foshan Hospital of TCM,Foshan 528000,China;The Eighth Clinical Medical College of Guangzhou University of Traditional Chinese Medicine,Foshan 528000,China)

机构地区：[1]佛山市中医院皮肤科,广东佛山528000 [2]广州中医药大学第八临床医学院,广东佛山528000

出　　处：《临床皮肤科杂志》2024年第8期458-461,共4页Journal of Clinical Dermatology

摘　　要：目的:探讨发疹性假性血管瘤病的临床、皮肤镜及组织病理特点。方法:回顾性分析佛山市中医院皮肤科门诊2020年9月-2022年11月诊治的14例发疹性假性血管瘤病成人患者的临床表现、皮肤镜及组织病理特征。结果:14例患者中男11例,女3例,年龄25~56岁。所有患者发病前均无明显前驱症状,7例(50%)在6月份发病,皮疹持续时间2 d~3个月。8例(57.14%)皮疹累及四肢,3例(21.43%)皮疹伴有瘙痒。6例(42.86%)行血常规、超敏C反应蛋白检查未见异常,其余8例未检查。14例患者均行皮肤镜检查,显示淡红色背景,毛细血管扩张,玻片压后毛细血管消退。4例患者行组织病理检查,显示真皮浅层血管扩张,部分血管内皮细胞肿胀突入管腔,未见血管增生。结论:发疹性假性血管瘤病成人患者发病前无明显前驱症状,发病有一定季节规律,可能和夏季炎热气候或蚊子叮咬诱发有关,皮疹常累及四肢,多无自觉症状,皮肤镜及组织病理检查有助于明确诊断。Objective:To explore the clinical,dermatoscopic and histopathological characteristics of eruptive pseudoangiomatosis(EPA).Methods:The clinical manifestations,dermatoscopic and histopathological features of 14 adult patients with EPA in the department from September 2020 to November 2022 were retrospectively analyzed.Results:Among the 14 adult patients,11 were male and 3 were female,aged 25 to 56 years.No obvious prodromal symptoms were reported before the onset of the disease.Seven patients(50%)developed the disease in June.The duration of rash was from two days to three months.Eight patients(57.14%)had the rash involving the limbs,and three patients(21.43%)had skin rash accompanied by pruritus.Six patients(42.86%)received normal blood routine test and hypersensitive C-reactive protein test,and the other eight patients were not examined.Dermatoscopy was performed in all 14 patients,showing light red background,capillary dilation,and capllary regression after slide compression.Histopathological examination was performed in four patients,and the results showed that the superficial dermal vessels expanded,some vascular endothelial cells swelled and protruded into the vascular cavity,and no vascular proliferation was found.Conclusion:Adult patients with EPA have no obvious prodromal symptoms before onset.The onset may be induced by hot summer weather or mosquito bite,making EPA seasonal.The rash often affects the limbs,and most of the patients are not conscious of symptoms.Dermatoscopic and histopathological examination should be conducted to make a clear diagnosis.

关 键 词：血管瘤病 假性 发疹性 皮肤镜 组织病理 

分 类 号：R732.2[医药卫生—肿瘤]