胃肠癌患者腹腔镜术后发生PE的危险因素分析  

Analysis of Risk Factors for Postoperative PE in Patients with Gastrointestinal Cancer Underwent Laparoscopic Surgery

作　　者：焦璐璐 陶丽 万利娟 JIAO Lulu;TAO Li;WAN Lijuan(Zhengzhou University Affiliated Cancer Hospital(Henan Cancer Hospital),Zhengzhou,450000)

机构地区：[1]郑州大学附属肿瘤医院,河南省肿瘤医院,450000

出　　处：《实用癌症杂志》2024年第9期1555-1559,共5页The Practical Journal of Cancer

摘　　要：目的探讨胃肠癌患者行腹腔镜术后发生肺栓塞(PE)的危险因素。方法选取行腹腔镜手术治疗的胃肠癌患者852例为研究对象,根据其术后是否发生PE分为PE组和非PE组。收集所有患者的临床资料,采用Logistic回归模型分析胃肠癌患者腹腔镜术后发生PE的危险因素。结果852例胃肠癌患者中共有68例发生PE,PE发生率为7.98%(68/852)。PE组年龄≥60岁、术中气腹压力>15 mmHg、术后卧床时间≥3 d、有脑梗死病史、合并糖尿病、合并冠心病、合并下肢深静脉血栓者占比高于非PE组及手术时间长于非PE组,差异均有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,年龄≥60岁、手术时间长、术中气腹压力>15 mmHg、术后卧床时间≥3 d、有脑梗死病史、合并糖尿病、合并冠心病、合并下肢深静脉血栓均是导致胃肠癌患者腹腔镜术后发生PE的独立危险因素(P<0.05)。结论年龄≥60岁、手术时间长、术中气腹压力>15 mmHg、术后卧床时间≥3 d、有脑梗死病史、合并糖尿病、合并冠心病、合并下肢深静脉血栓均是导致胃肠癌患者腹腔镜术后发生PE的危险因素,临床应加大对具备上述特征的胃肠癌患者关注度,及早做好干预治疗,以预防或减少PE发生,改善患者预后。Objective To explore the risk factors of pulmonary embolism(PE)after laparoscopic surgery in patients with gastrointestinal cancer.Methods 852 patients with gastrointestinal cancer who underwent laparoscopy were collected as the study subjects.According to whether PE occurred after surgery,they were grouped into PE group and non PE group.Clinical data were collected from all patients,and Logistic regression analysis models were applied to analyze the risk factors for postoperative PE in patients with gastrointestinal cancer underwent laparoscopic surgery.Results A total of 68 out of 852 patients with gastrointestinal cancer developed PE,with a PE incidence rate of 7.98%(68/852).The proportions of patients with age≥60 years,intraoperative pneumoperitoneum pressure>15 mmHg,postoperative bed rest time≥3 days,history of cerebral infarction,combined with diabetes,combined with coronary heart disease,combined with lower limb deep vein thrombosis were higher than that in the non PE group,and the operation time in PE group were longer than those in non PE group,the differences are statistically significant(P<0.05).Multivariate Logistic regression analysis showed that age≥60 years,long operation time,intraoperative pneumoperitoneum pressure>15mmHg,postoperative bed rest time≥3 days,history of cerebral infarction,combined with diabetes,combined with coronary heart disease,combined with lower limb deep vein thrombosis were all independent risk factors for PE after laparoscopic surgery in patients with gastrointestinal cancer(P<0.05).Conclusion Age≥60 years,long operation time,intraoperative pneumoperitoneum pressure>15 mmHg,postoperative bed rest time≥3 days,history of cerebral infarction,combined with diabetes,combined with coronary heart disease,combined with lower limb deep vein thrombosis are all risk factors for PE after laparoscopic surgery in patients with gastrointestinal cancer.In clinical practice,attention should be paid to patients with gastrointestinal cancer who possess the above characteristics,an

关 键 词：胃肠癌 肺栓塞 腹腔镜 危险因素 

分 类 号：R735.2[医药卫生—肿瘤] R735.3[医药卫生—临床医学]