AEEG结合脑干听觉诱发电位表现与昏迷患者预后的相关性分析  

Analysis of the correlation between AEEG combined with brain-stem auditory evoked potential and prognosis of coma patients

作　　者：李深 李瑾 LI Shen;LI Jin(Zhoukou Hospital of Traditional Chinese Medicine,Zhoukou 466000,China;The Third Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)

机构地区：[1]周口市中医院,河南周口466000 [2]郑州大学第三附属医院,河南郑州450000

出　　处：《中国实用神经疾病杂志》2024年第8期1018-1022,共5页Chinese Journal of Practical Nervous Diseases

基　　金：漯河医专科技创新项目(编号:2023ZD45)。

摘　　要：目的探讨动态脑电图(AEEG)结合脑干听觉诱发电位(BAEP)表现与昏迷患者预后的相关性。方法回顾性研究2023-01—2024-01周口市中医院神经内科收治的60例昏迷患者的临床资料,60例患者均行AEEG、BAEP检查,连续随访3个月,采用格拉斯哥预后量表(GOS)评估预后情况,分为预后良好组(GOS评分3~5分)32例,预后不良组(GOS评分1~2分)28例,分析AEEG、BAEP检查对患者预后的评估价值,采用Spearman相关性分析法探讨AEEG、BAEP与GOS评分的相关性。结果联合检查的准确性较AEEG、BAEP单独检查高,敏感性较BAEP单独检查高(P<0.05);联合检查的敏感性与AEEG单独检查比较差异无统计学意义(P>0.05),特异性与AEEG、BAEP单独检查比较差异无统计学意义(P>0.05);Spearman相关性分析显示,AEEG、BAEP分级与3个月后的GOS评分均呈负相关(r=-0.720、-0.650,P<0.05)。结论AEEG联合BAEP检查对昏迷患者预后具有较高的预测效能,且AEEG、BAEP分级与昏迷患者的预后均呈负相关。Objective To investigate the correlation between the performance of ambulatory electroencephalography(AEEG)combined with brain-stem auditory evoked potential(BAEP)and the prognosis of coma patients.Methods Clinical data of 60 coma patients admitted to the Department of Neurology of Zhoukou Hospital of Traditional Chinese Medicine from January 2023 to January 2024 were retrospectively studied.All 60 patients underwent AEEG and BAEP examinations,and were followed up for 3 months.Based on the Glasgow outcome scale(GOS)score,they were divided into the good prognosis group(GOS 3-5)of 32 cases and the poor prognosis group(GOS 1-2)of 28 cases.The evaluation value of AEEG and BAEP examinations on patients’prognosis was analyzed,and Spearman correlation analysis was used to investigate the correlations among AEEG,BAEP,and GOS score.Results The accuracy and sensitivity of the combined of AEEG and BAEP examination were higher than those of AEEG and BAEP alone(P<0.05).There was no significant difference in sensitivity between combined examination and AEEG alone(P>0.05).There was no significant difference in specificity among specific AEEG and BAEP alone,combined examination(P>0.05).According to Spearman correlation analysis,there was a negative correlation between AEEG grading and GOS score after 3 months in coma patients(r=-0.720,P<0.050).According to Spearman correlation analysis,there was a negative correlation(r=-0.650,P<0.050)between the BAEP grading of coma patients and the GOS score after 3 months.Conclusion The combination of AEEG and BAEP has a high value in evaluating the prognosis of coma patients,and the grading of AEEG and BAEP is negatively correlated with the prognosis of coma patients.

关 键 词：昏迷 动态脑电图 脑干听觉诱发电位 预后 相关性 

分 类 号：R741.044[医药卫生—神经病学与精神病学]