Exogenous electric field to accelerate wound healing  

作　　者：Kai-Qi Yang Jia Chen Xiao-Mei Li Si-Yuan Chang Yan-Jun Yang Yan-Ling Hu 

机构地区：[1]College of Material Engineering,Fujian Agriculture and Forestry University,Fuzhou 350108 [2]China.2Medical Science and Technology Innovation Center,School of Radiology,Shandong First Medical University&Shandong Academy of Medical Sciences,Tai’an 271016 [3]China.3School of Basic Medicine,Medical College of Putian University,Putian 351100 [4]China.4College of Life and Health,Nanjing Polytechnic Institute,Nanjing 210048 [5]China.5School of Electrical and Computer Engineering,College of Engineering,The University of Georgia,Athens 30602,USA.

出　　处：《Biomedical Engineering Communications》2024年第3期1-2,共2页生物医学工程通讯

基　　金：supported by the Natural Science Foundation of Jiangsu Province(BK20230117);the Natural Science Research Project of Nanjing Polytechnic Institute(NJPI-2023-04);the Startup Fund for Advanced Talents of Putian University(Grant No.2021070);the Qinglan Project of Jiangsu Province.

摘　　要：Wound healing is a critical physiological process in living organisms that includes repair cell proliferation and migration,etc.[1,2].While effective wound-healing treatment strategies have been developed in the past,few have actively controlled the behavior of skin cells to accelerate wound healing[3,4].The importance of accelerated wound healing lies in its ability to shorten treatment time,reduce the risk of infection,and lower the cost of treatment.Electrical stimulation can modulate cell behavior during wound healing by simulating endogenous electric fields,boosting cell migration,fibroblast proliferation,and granulation tissue growth more significantly than traditional methods[5-7].However,electrical stimulation devices’size,space limitations,and unsustainability make them challenging to use in clinical surgery,hindering real-time and convenient treatment.It is therefore crucial to explore the miniaturization of electrical stimulation devices to advance the healing of skin wounds in clinical procedures.Recently,Chen et al.report a flexible micro-Zn-MnO2(mZMB)battery-based woundplast for wound management,which shows a promising path in biomedical applications(Figure 1)[8].

关 键 词：HEALING WOUND STIMULATION 

分 类 号：R73[医药卫生—肿瘤]