临床孤立综合征  

Clinically isolated syndrome

作　　者：冯慧宇[1] 黄鑫[1] Feng Huiyu;Huang Xin(Department of Neurology,the First Affiliated Hospital of Sun Yat-sen University,Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases,National Key Clinical Department and Key Discipline of Neurology,Guangzhou 510080,China)

机构地区：[1]中山大学附属第一医院神经科,广东省重大神经疾病诊治研究重点实验室,国家临床重点专科和国家重点学科,广州510080

出　　处：《中华神经科杂志》2024年第8期900-906,共7页Chinese Journal of Neurology

摘　　要：多发性硬化(MS)是一种以中枢神经系统白质炎性脱髓鞘为主要病理特点的自身免疫疾病。大部分MS是以临床孤立综合征(CIS)起病。文中就CIS转归为MS的识别及管理进行阐述,旨在帮助临床医师尽早识别转归危险因素,并全面评估、权衡利弊,及时准确启动疾病修饰治疗,延缓疾病进程。Multiple sclerosis(MS)is an autoimmune disease characterized by central nervous system white matter inflammatory demyelination.Most MS starts with clinically isolated syndrome(CIS).This article summarizes the identification and management of CIS converted to MS,which helps clinicians identify prognosis risk factors as soon as possible,and evaluate the disease comprehensively,initiate the disease modified therapy promptly and accurately,so that to delay the progression of the disease.

关 键 词：多发性硬化 临床孤立综合征 疾病修正治疗 

分 类 号：R744.51[医药卫生—神经病学与精神病学]