小脑齿状核脑深部电刺激术对脑卒中后运动功能的改善作用  

Prospects of dentate nucleus deep brain stimulation for poststroke motor recovery

作　　者：孟凡刚[1] 许天奇 季玉陈 张树新 MENG Fan-gang;XU Tian-qi;JI Yu-chen;ZHANG Shu-xin(Beijing Neurosurgical Institute,Department of Neurosurgery,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China;Department of Neurosurgery,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,He'nan,China;Department of Neurosurgery,Dong'e County People's Hospital,Liaocheng 252201,Shandong,China)

机构地区：[1]北京市神经外科研究所、首都医科大学附属北京天坛医院神经外科,100070 [2]郑州大学第一附属医院神经外科,450052 [3]山东省东阿县人民医院神经外科,聊城252201

出　　处：《中国现代神经疾病杂志》2024年第7期507-509,共3页Chinese Journal of Contemporary Neurology and Neurosurgery

基　　金：河南省重点研发专项项目(项目编号:241111310100)。

摘　　要：脑卒中可以导致长期运动障碍,降低生活质量。尽管传统康复治疗取得的进展为患者带来曙光,仍有众多患者面临康复治疗效果有限的问题。神经调控技术即显示出突破性治疗潜力。本文旨在概述脑卒中后神经可塑性机制,探究小脑齿状核脑深部电刺激术改善脑卒中后运动功能的作用机制、总结研究进展,以为临床实践提供科学依据及新的治疗视角。Stroke can lead to long-term motor disorders and reduced quality of life.Despite advances in conventional rehabilitation,many patients are still faced with limited efficacy of rehabilitation.Neuromodulation techniques have shown breakthrough therapeutic potential.The purpose of this article is to provide an overview of the mechanism of poststroke neuroplasticity,to explore the mechanism of dentate nucleus deep brain stimulation(DN-DBS)to improve poststroke motor function,and to summarize the progress of the study,in order to provide a scientific basis and a new therapeutic perspective for clinical practice of DN-DBS.

关 键 词：深部脑刺激法 小脑核 卒中 运动障碍 

分 类 号：R743.3[医药卫生—神经病学与精神病学]