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作 者:田书亚[1] 王瑞涛[1] 余阳[1] TIAN Shuya;WANG Ruitao;YU Yang(Interventional Operating Room,the Second Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,He’nan,China)
机构地区:[1]郑州大学第二附属医院介入手术室,郑州4500000
出 处:《癌症进展》2024年第13期1448-1450,1469,共4页Oncology Progress
基 金:河南省医学科技攻关计划联合共建项目(LHGJ20220513)。
摘 要:目的探讨正念减压疗法(MBSR)在支架植入术治疗晚期肝癌合并冠心病患者中的应用效果。方法根据干预方法的不同将90例晚期肝癌合并冠心病患者分为对照组(n=48)和MBSR组(n=42),对照组患者采取常规干预,MBSR组患者在对照组的基础上采取MBSR干预。比较两组患者的自我感受负担[自我感受负担量表(SPBS)]、生活质量[肝病患者生命质量测定量表(LDQOL)]及心血管不良事件发生情况。结果干预后,两组患者SPBS各维度评分均低于本组干预前,MBSR组患者SPBS各维度评分均低于对照组,差异均有统计学意义(P﹤0.05)。干预后,两组患者LDQOL各维度评分均高于本组干预前,MBSR组患者LDQOL各维度评分均高于对照组,差异均有统计学意义(P﹤0.05)。术后3个月,MBSR组患者心血管不良事件总发生率低于对照组,差异有统计学意义(P﹤0.05)。结论MBSR应用于支架植入术治疗的晚期肝癌合并冠心病患者,可降低自我感受负担,提高生活质量,减少心血管不良事件。Objective To explore the application effect of mindfulness-based stress reduction(MBSR)in advanced liver cancer patients complicated with coronary heart disease undergoing stent implanting.Method According to different intervention methods,90 patients with advanced liver cancer complicated with coronary heart disease were divided into control group(n=48)and MBSR group(n=42).Patients in the control group received routine intervention,and patients in the MBSR group received MBSR intervention on the basis of the control group.The self-perceived burden[self-perceived burden scale(SPBS)],quality of life[liver disease quality of life instrument(LDQOL)]and cardiovascular adverse events were compared between the two groups.Result After intervention,the scores of each dimension of SPBS in both groups were lower than those before intervention,and the scores of each dimension of SPBS in MBSR group were lower than those in control group,and the differences were statistically significant(P<0.05).After intervention,the scores of each dimension of LDQOL in both groups were higher than those before intervention,the scores of each dimension of LDQOL in MBSR group were higher than those in control group,and the differences were statistically significant(P<0.05).Three months after surgery,the total incidence of cardiovascular adverse events in MBSR group was lower than that in control group,and the difference was statistically significant(P<0.05).Conclusion MBSR can reduce the selfperceived burden,improve the quality of life and reduce cardiovascular adverse events in patients with advanced liver cancer complicated with coronary heart disease treated by stent implantation.
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