综合干预对年轻卵巢癌术后腹腔灌注化疗患者应对方式及生活质量的影响  

Effect of comprehensive intervention on coping style and quality of life of young ovarian cancer patients undergoing postoperative intraperitoneal perfusion chemotherapy

作　　者：马润红 李晓柳 赵丹 刘攀攀 冯宪凌 MA Runhong;LI Xiaoliu;ZHAO Dan;LIU Panpan;FENG Xianling(Department of Gynecology,He’nan Provincial Key Medicine Laboratory of Nursing,He’nan Provincial People’s Hospital,Zhengzhou University People’s Hospital,Zhengzhou 450000,He’nan,China)

机构地区：[1]河南省人民医院妇科,河南省护理医学重点实验室,郑州大学人民医院,郑州4500000

出　　处：《癌症进展》2024年第13期1499-1503,共5页Oncology Progress

摘　　要：目的探讨综合干预对年轻卵巢癌术后腹腔灌注化疗患者应对方式及生活质量的影响。方法依据干预方式的不同将78例年轻卵巢癌术后腹腔灌注化疗患者分为常规组(n=37)和观察组(n=41),常规组患者采取常规干预,观察组患者采取综合干预。比较两组患者的心理状态[抑郁自评量表(SDS)、焦虑自评量表(SAS)]、应对方式[医学应对方式问卷(MCMQ)]、生活质量[欧洲癌症研究与治疗组织生命质量测定量表(EORTC QLQ-C30)]及不良反应发生情况。结果干预后,两组患者SDS、SAS评分均低于本组干预前,观察组患者SDS、SAS评分均低于常规组,差异均有统计学意义(P﹤0.05)。干预后,两组患者面对评分均高于本组干预前,回避、屈服评分均低于本组干预前,观察组患者面对评分高于常规组,回避、屈服评分均低于常规组,差异均有统计学意义(P﹤0.05)。干预后,两组患者EORTC QLQ-C30各维度评分均高于本组干预前,观察组患者EORTC QLQ-C30各维度评分均高于常规组,差异均有统计学意义(P﹤0.05)。观察组患者的不良反应总发生率为14.63%,明显低于常规组的54.05%,差异有统计学意义(P﹤0.01)。结论综合干预可改善年轻卵巢癌术后腹腔灌注化疗患者的负性情绪,提高积极应对水平和生活质量,降低不良反应发生率。Objective To explore the effect of comprehensive intervention on coping style and quality of life of young ovarian cancer patients undergoing postoperative intraperitoneal perfusion chemotherapy.Method A total of 78 young ovarian cancer patients undergoing postoperative intraperitoneal perfusion chemotherapy were divided into conventional group(n=37)and observation group(n=41)based on different intervention methods.The conventional group received routine intervention,while the observation group received comprehensive intervention.The psychological status[self-rating depression scale(SDS),self-rating anxiety scale(SAS)],coping style[medical coping mode questionnaire(MCMQ)],quality of life[European Organization for Research and Treatment of Cancer quality of life questionnaire core 30(EORTC QLQ-C30)],and incidence of adverse reactions were compared between the two groups.Result After intervention,the SDS and SAS scores of both groups were lower than those before intervention,the SDS and SAS scores of the observation group were lower than those of the conventional group,and the differences were statistically significant(P<0.05).After intervention,the confrontation scores of both groups were higher than those before intervention,the avoidance and surrender scores of both groups were lower than those before intervention,the confrontation score of the observation group was higher that of the conventional group,and the avoidance and surrender scores of the observation group were lower than those of the conventional group,and the differences were statistically significant(P<0.05).After intervention,the scores of all dimensions of EORTC QLQ-C30 in both groups were higher than those before intervention,the scores of all dimensions of EORTC QLQ-C30 in the observation group were higher than those in the conventional group,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the observation group was 14.63%,which was lower than 54.05%in the conventional group,and the differenc

关 键 词：卵巢癌 腹腔灌注化疗 综合干预 生活质量 不良反应 

分 类 号：R737.31[医药卫生—肿瘤]