子午流注择时五行音乐疗法联合阿戈美拉汀治疗老年广泛性焦虑障碍的效果及对生活质量的影响  

Curative effect of midnight-noon ebb-flow acupoint selection five element music therapy combined with agomelatine on quality of life ofthe elderly with generalized anxiety disorder

作　　者：于兴晨 张津金 潘乾坤 武业琛 杨洪敬 巨星[1] 李佳音 张铮 庞堃[1] 贾铎 杨桂君[1] 王兴生[1] YU Xingchen;ZHANG Jinjin;PAN Qiankun;WU Yechen;YANG Hongjing;JU Xing;LI Jiayin;ZHANG Zheng;PANG Kun;JIA Duo;YANG Guijun;WANG Xingsheng(Fourth Department of Clinical,Qinhuangdao Jiulongshan Hospital,Qinhuangdao,Hebei 066000)

机构地区：[1]河北省秦皇岛市九龙山医院临床四科,河北秦皇岛066000

出　　处：《河北中医》2024年第8期1301-1304,共4页Hebei Journal of Traditional Chinese Medicine

基　　金：秦皇岛市重点研发计划科技支撑项目(编号:202301A151)。

摘　　要：目的观察子午流注择时五行音乐疗法联合阿戈美拉汀治疗老年广泛性焦虑障碍的效果及对生活质量的影响。方法将120例老年广泛性焦虑障碍患者按照随机数字表法分为2组,对照组58例(最终完成治疗49例)采用阿戈美拉汀治疗,治疗组62例(最终完成治疗52例)在对照组治疗基础上联合子午流注择时五行音乐疗法,2组治疗时间均为1个月。比较2组治疗前后汉密尔顿焦虑量表(HAMA)评分、汉密尔顿抑郁量表(HAMD)评分变化;比较2组临床疗效总评量表(CGI)评分变化;比较2组不良反应的发生情况。统计2组临床疗效。结果治疗组总有效率94.23%(49/52),对照组总有效率79.59%(39/49),治疗组疗效优于对照组(P<0.05)。2组治疗后HAMA、HAMD评分较本组治疗前降低(P<0.05);治疗后治疗组HAMA、HAMD评分低于对照组(P<0.05)。治疗组治疗后SI、GI评分均低于对照组(P<0.05),EI高于对照组(P<0.05)。2组不良反应总发生率比较差异无统计学意义(P>0.05)。结论子午流注择时五行音乐疗法联合阿戈美拉汀治疗老年广泛性焦虑障碍效果显著,可有效改善患者的不良情绪,且不会增加不良反应的发生。Objective To observe the curative effect of midnight-noon ebb-flow acupoint selection five element music therapy combined with agomelatine on quality of life ofthe elderly patients with generalized anxiety disorder(GAD).Methods A total of 120 elderly patients with GAD were randomly assigned into treatment group(n=52,10 cases dropped off)and control group(n=49,9 cases dropped off).All patients were managed by agomelatine,and those in treatment group were additionally treated with midnight-noon ebb-flow acupoint selection five element music therapy.A 1-month treatment was performed to compare Hamilton Anxiety Scale(HAMA)and Hamilton Depression Scale(HAMD)scores,Clinical Global Impression Scale(CGI)scores,incidence of adverse reactions.The curative effect was assessed.Results The overall effective rate in the treatment group was better than that in the control group(94.23%[49/52]vs 79.59%[39/49],P<0.05).After treatment,HAMA and HAMD scores in the both groups were significantly decreased(P<0.05),which decreased notably in the treatment group compared with the control group(P<0.05).After treatment,significantly lower severity of illness(SI)and global improvement(GI)scores,and significantly higher efficacy index(EI)were found in treatment group than those of control group(all P<0.05).The overall incidence of adverse reactions between the two groups was comparable(P>0.05).Conclusion The midnight-noon ebb-flow acupoint selection five element music therapy combined with agomelatine has a significant effect in the elderly with GAD,which can effectively improve negative emotions,and without increasing adverse reactions.

关 键 词：广泛性焦虑障碍 老年人 子午流注择时 五行音乐疗法 

分 类 号：R749.72[医药卫生—神经病学与精神病学]