高度近视与原发性开角型青光眼临床特征的研究进展  

Progress of clinical features of high myopia and primary open angle glaucoma

作　　者：王雪[1,2,3] 吕洋 Wang Xue;Lyu Yang(Ophthalmology Center,the 940th Hospital of Joint Logistic Support Forceof the Chinese People's Liberation Army,Lanzhou 730000,Gansu Province,China;First School of Clinical Medical,Gansu University of ChineseMedicine,Lanzhou 730000,Gansu Province,China;Basic MedicalLaboratory,the 940th Hospital of the Joint Logistic Force of the Chinese People's Liberation Army,Gansu Key Laboratory of Stem Cells and GeneDrugs,Lanzhou 730050,Gansu Province,China)

机构地区：[1]中国人民解放军联勤保障部队第九四○医院眼科中心,中国甘肃省兰州市730000 [2]甘肃中医药大学第一临床医学院,中国甘肃省兰州市730000 [3]中国人民解放军联勤保障部队第九四○医院基础医学实验室、甘肃省干细胞与基因药物重点实验室,中国甘肃省兰州市730050

出　　处：《国际眼科杂志》2024年第9期1403-1407,共5页International Eye Science

基　　金：国家自然科学基金资助项目(No.82000926);甘肃省卫生健康委员基金资助项目(No.GSWSKY2022-05);联勤保障部队第九四○医院院基金(No.2021yxky033,2023TXKT011,2023YXKY033)。

摘　　要：随着人们生活方式的显著改变,全球近视患病率日益上升,引发了临床医生的密切关注。近视易合并其他严重的眼科疾病,尤其是高度近视(HM)患者,常合并原发性开角型青光眼(POAG),其发病率远远高于屈光状态正常的人群。当高度近视与原发性开角型青光眼并存时,病情变得尤其复杂。近年我们在临床工作中集中关注患者的眼底改变特征。从高度近视人群中早期发现原发性开角型青光眼患者,这是对两种疾病深入了解并进行有效防治的关键。文章通过回顾分析近年文献,从流行病学、发病机制及临床特征方面对高度近视与原发性开角型青光眼的关系及研究进展进行综述,以期为疾病早期发现、早期诊断、早期治疗提供帮助。With the significant changes in people’s lifestyles,the prevalence of myopia is escalating globally,which has aroused the close attention of clinicians.Myopia is easy to combine with other serious ophthalmic diseases,especially in patients with high myopia(HM),often combined with primary open angle glaucoma(POAG),and the incidence rate is much higher than that of people with normal refractive status.The condition becomes especially complex when HM co-exists with POAG.In recent years,we have focused on the characteristics of fundus changes in patients in clinical work.Early detection of patients with POAG from HM is the key to in-depth understanding and effective prevention and treatment of these two diseases.In this paper,we review the recent literatures on the relationship between HM and POAG from the aspects of epidemiology,pathogenesis,and clinical features,and summarize the research progress,so as to provide help for early detection,early diagnosis,and early treatment of the disease.

关 键 词：近视 高度近视 青光眼 原发性开角型青光眼(POAG) 筛板 视盘 视网膜神经纤维层 眼压 光学相干断层扫描血管成像技术(OCTA) 

分 类 号：R778.11[医药卫生—眼科] R775.2[医药卫生—临床医学]