LVIS支架辅助Target弹簧圈栓塞治疗颅内微小动脉瘤47例效果观察  

Efficacy of LVIS stent-assisted Target coil embolization in treatment of very small intracranial aneurysms:An analysis of 47 cases

作　　者：徐洪章 张照龙 徐锐[1] XU Hongzhang;ZHANG Zhaolong;XU Rui(Interventional Medicine Center,The Affiliated Hospital of Qingdao University,Qingdao 266003,China)

机构地区：[1]青岛大学附属医院介入医学中心,山东青岛266003 [2]荣成市石岛人民医院CT室

出　　处：《精准医学杂志》2024年第4期333-336,共4页Journal of Precision Medicine

摘　　要：目的评估LVIS支架辅助Target弹簧圈栓塞颅内微小动脉瘤的临床效果。方法回顾性分析2015年7月—2023年5月我中心采用LVIS支架辅助Target弹簧圈介入栓塞的47例微小动脉瘤患者的临床资料及随访结果。结果47例患者术后即刻造影显示致密栓塞32例(68.1%),瘤颈残留11例(23.4%),部分栓塞4例(8.5%)。围手术期并发症4例(8.5%),包括2例破裂动脉瘤发生术中出血(1例死亡,1例致密栓塞后无明显后遗症),1例破裂动脉瘤术后合并颅内感染(抗感染治疗后无神经系统功能缺损),1例术中血栓形成(术中应用替罗非班后无神经系统功能缺损)。33例患者进行了影像学随访,其中动脉瘤完全闭塞29例(87.9%),动脉瘤稳定4例(12.1%)。随访过程中1例患者出院14 d后颞叶出血死亡,余患者无再出血发生。结论LVIS支架辅助Target弹簧圈栓塞颅内微小动脉瘤较为安全、有效,适合在临床推广使用。Objective To investigate the efficacy of LVIS stent-assisted Target coil embolization in the treatment of very small intracranial aneurysms.Methods A retrospective analysis was performed for the clinical data and follow-up results of 47 patients with very small intracranial aneurysms who underwent LVIS stent-assisted Target coil embolization in our center from July 2015 to May 2023.Results For the 47 patients,angiography immediately after surgery showed dense embolization in 32 patients(68.1%),residual aneurysm neck in 11 patients(23.4%),and partial embolization in 4 patients(8.5%).Perioperative complication was observed in 4 patients(8.5%),among whom 2 had intraoperative bleeding due to ruptured aneurysms(1 died and 1 had no obvious sequela after dense embolization),1 had intracranial infection after ruptured aneurysm surgery(with no neurolo-gical deficit after anti-infective therapy),and 1 had thrombosis during surgery(with no neurological deficit after the intraoperative application of tirofiban).Radiological follow-up examination was performed for 33 patients,among whom 29(87.9%)achieved complete embolization of aneurysms and 4(12.1%)had stable aneurysms.During follow-up,1 patient died due to temporal lobe hemorrhage after 14 days of discharge,while the other patients did not experience rebleeding.Conclusion LVIS stent-assisted Target coil embolization is safe and effective in the treatment of very small intracranial aneurysms,and therefore,it holds promise for clinical application.

关 键 词：颅内动脉瘤 栓塞 治疗性 血管内操作 支架 治疗结果 

分 类 号：R743.9[医药卫生—神经病学与精神病学] R651.122[医药卫生—临床医学]