^(18)F-FDG PET/CT与肿瘤标志物NSE和ProGRP在小细胞肺癌诊疗中的应用  

The application of ^(18)F-FDG PET/CT with tumor markers NSE and ProGRP in the diagnosis and treatment of small cell lung cancer

作　　者：林帅 王艳丽 LIN Shuai;WANG Yanli(PET/CT Center,Department of Molecular Imaging,Qingdao Central Hospital,Qingdao 266042,China)

机构地区：[1]青岛市中心医院分子影像科PET/CT中心,山东青岛266042

出　　处：《精准医学杂志》2024年第4期371-373,375,共4页Journal of Precision Medicine

基　　金：青岛市医药卫生科研计划项目(2021-WJZD067)。

摘　　要：小细胞肺癌(small cell lung cancer,SCLC)是肺内最常见的神经内分泌肿瘤,恶性程度高,易复发、易转移。改善SCLC患者预后的关键在于疾病的早期诊断、正确分期以及准确评估疗效和预后。本文通过对^(18)F-氟代脱氧葡萄糖(FDG)PET/CT、肿瘤标志物神经元特异性烯醇化酶(NSE)和胃泌素释放肽前体(ProGRP)在SCLC诊疗方面的应用进展进行综合分析,以期为临床上SCLC患者的诊疗提供帮助。Small cell lung cancer(SCLC)is the most common neuroendocrine tumor in the lungs.SCLC is characterized by high malignancy and high recurrence and metastasis rates.The improvement of the prognosis of patients with SCLC relies on early diagnosis,correct staging,and accurate assessment of efficacy and prognosis.In this paper,we comprehensively analyze the application progress of ^(18)F-fluorodeoxyglucose(FDG)PET/CT as well as the tumor markers neuron-specific enolase(NSE)and gastrin-releasing peptide precursor(ProGRP)in the diagnosis and treatment of SCLC.Our results can be useful for the diagnosis and treatment of SCLC patients in clinical practice.

关 键 词：小细胞肺癌 氟脱氧葡萄糖F18 正电子发射断层显像计算机体层摄影术 磷酸丙酮酸水合酶 胃泌素释放肽 蛋白质前体 生物标记 肿瘤 

分 类 号：R734.2[医药卫生—肿瘤]