不同阿托品浓度治疗近视性屈光不正儿童近视的对比研究  

Comparative Study of Different Concentrations of Atropine in the Treatment of Myopia in Children with Myopic Ametropia

作　　者：李静文 谢慧[1] 李娟[1] LI Jing-wen;XIE Hui;LI Juan(Ophthalmology Department,Jiaozuo People's Hospital,Jiaozuo 454000,Henan Province,China)

机构地区：[1]焦作市人民医院眼科,河南焦作454000

出　　处：《罕少疾病杂志》2024年第8期29-30,共2页Journal of Rare and Uncommon Diseases

摘　　要：目的研究不同阿托品浓度对近视性屈光不正儿童近视进展的影响。方法选取2021年1月至2022年12月间我院收治的80例近视性屈光不正儿童作为研究对象。随机将患者分为低浓度组(n=40,给予0.01%阿托品滴眼液)和高浓度组(n=40,给予1.0%阿托品滴眼液)。分析比较两组治疗前后屈光度、眼轴、眼压以及不良反应发生率。结果治疗后与治疗前相比,两组的屈光度、眼轴、眼压均有显著改善(P<0.05);但组间的屈光度、眼轴、眼压对比均无显著差异(P>0.05)。低浓度组的口干、视物模糊、皮肤干燥和畏光不良反应发生率(5.00%)明显低于高浓度组(20.00%)(P<0.05)。结论0.01%与1.0%的阿托品滴眼液均有助于改善儿童的屈光度、眼轴、眼压,但低浓度阿托品滴眼液治疗的不良反应发生率更低。Objective To study the effect of different concentrations of atropine on myopia progression in children with myopic ametropia.Methods Eighty children with myopic ametropia who were admitted to the hospital from January 2021 to December 2022 were selected,and randomly divided into the low concentration group(40 children treated with 0.01%atropine eye drops)and the high concentration group(40 children treated with 1.0%atropine eye drops).The two groups were compared on diopter,axis oculi,intraocular pressure,and the incidence of adverse reactions.Results After treatment,diopter,axis oculi and intraocular pressure of both groups were significantly improved(P<0.05),but there was no significant difference in these indicators between the groups(P>0.05).The incidence of adverse reactions in the low concentration group(5.00%)was significantly lower than that in the high concentration group(20.00%)(P<0.05).Conclusion Both 0.01%atropine eye drops and 1.0%atropine eye drops are helpful for improving diopter,axis oculi and intraocular pressure of children with myopic ametropia,but the incidence of adverse reactions to low concentration is lower.

关 键 词：阿托品 近视性屈光不正 儿童 近视进展 

分 类 号：R77[医药卫生—眼科]