荆花胃康、复合乳酸菌及三联疗法治疗HP感染患者的临床疗效及对不良反应的影响  

Clinical Efficacy and Adverse Reactions of Jinghua Weikang,Combined Lactic Acid Bacteria and Triple Therapy in the Treatment of Hp Infection

作　　者：翟恒勇 张东丽[1] 刘翠霞[1] 赵治彬[1] ZHAI Heng-yong;ZHANG Dong-li;LIU Cui-xia;ZHAO Zhi-bin(Department of Gastroenterology,Taizhou People’s Hospital,Taizhou 225300,Jiangsu Province,China Abstract:Objective To investigate the clinical efficacy and adverse reactions of Jinghua Weikang,combined)

机构地区：[1]泰州市人民医院消化内科,江苏泰州225300

出　　处：《罕少疾病杂志》2024年第8期108-110,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的探讨荆花胃康、复合乳酸菌及三联疗法治疗HP感染患者的临床疗效及对不良反应的影响。方法选取2017年1月至2019年10月我院收治的120例HP感染患者,根据随机数字表法分为A、B、C组,各40例。A组采用标准三联疗法,B组采用复合乳酸菌联合三联疗法,C组采用荆花胃康、复合乳酸菌联合三联疗法。将患者的幽门螺杆菌根除率、临床症状治疗效果及不良反应作为研究指标。结果治疗后,B、C组HP根除率明显高于A组(P<0.05);治疗后,B、C组较A组总有效率明显升高(P<0.05),且C组较B组总有效率明显升高(P<0.05);治疗后,三组较治疗前症状积分均明显降低(P<0.05),且B、C组较A组明显降低(P<0.05),C组较B组明显降低(P<0.05);治疗后,B、C组较A组不良反应总发生率明显降低(P<0.05)。结论荆花胃康、复合乳酸菌联合三联疗法在HP感染患者中的疗效显著,并且对于患者的症状改善有较好的作用,同时能明显清除幽门螺旋杆菌,在临床治疗上且安全有效。Objective To investigate the clinical efficacy and adverse reactions of Jinghua Weikang,combined lactic acid bacteria and triple therapy in the treatment of Helicobacter pylori(HP)infection.Methods From January 2017 to October 2019,a total of 120 patients diagnosed with Helicobacter pylori(HP)infection were admitted to our hospital.These patients were randomly divided into three groups(A,B,and C)using a random number table,with each group consisting of 40 patients.Group A received the standard triple therapy,while Group B was treated with a combination of compound lactobacillus and triple therapy.Group C received a combination of Jinghua Weikang,compound lactobacillus,and triple therapy.The study aimed to evaluate the eradication rate of Helicobacter pylori,the therapeutic effects on clinical symptoms,and the incidence of adverse reactions as the primary research indicators.Results After treatment,the eradication rates of Helicobacter pylori(HP)in groups B and C were significantly higher than that in group A(P<0.05).Additionally,the overall effective rates in groups B and C were markedly increased compared to group A(P<0.05),with group C showing a significantly higher overall effective rate than group B(P<0.05).Furthermore,the symptom scores for all three groups significantly decreased after treatment compared to before treatment(P<0.05).Notably,the symptom scores in groups B and C were significantly lower than those in group A(P<0.05),and group C had a significantly lower symptom score compared to group B(P<0.05).Lastly,the total incidence of adverse reactions in groups B and C was significantly lower than that in group A after treatment(P<0.05).Conclusion The combination of Jinghua Weikang and compound lactobacillus with triple therapy demonstrates significant efficacy in patients with Helicobacter pylori(HP)infection.This treatment not only effectively alleviates the symptoms of the patients but also significantly eradicates Helicobacter pylori.Furthermore,it is considered safe and effective for clinical appli

关 键 词：荆花胃康 复合乳酸菌 三联疗法 幽门螺杆菌 症状积分 

分 类 号：R573[医药卫生—消化系统]