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作 者:刘诚敬 LIU Cheng-jing(School of Medicine,Shihezi University,Shihezi 832000,Xinjiang Uygur Autonomous Region,China)
出 处:《罕少疾病杂志》2024年第8期156-158,共3页Journal of Rare and Uncommon Diseases
摘 要:卡波西肉瘤(kaposi's sarcoma,KS)是一种侵袭性淋巴血管增生性肿瘤。其发生与卡波西肉瘤相关疱疹病毒(kaposi sarcoma-associated herpesvirus,KSHV)有关,通常表现为皮肤和黏膜上的血管病变。KS在人类免疫缺陷病毒感染者及艾滋病患者中常见,是一种死亡率较高的恶性肿瘤,因此对于KS的致病原和治疗方式的研究有着重要意义。本文就卡波西肉瘤的现状、KS致病原KSHV病毒的结构、致病机制、传播途径以及对KS的治疗方式进行梳理探究和简要概述。Kaposi's sarcoma(KS)is an aggressive lymphatic endothelial cell proliferative tumor.Its occurrence is related to Kaposi sarcoma-associated herpesvirus(KSHV),and it is usually manifested as vascular lesions on the skin and mucosa.KS is common in human immunodeficiency virus(HIV)infected patients and AIDS patients,and it is a malignant tumor with a high mortality rate.Therefore,the study of the pathogen and treatment of KS is of great significance.This article provides a brief overview of the current situation of Kaposi's sarcoma,the structure,pathogenic mechanism,transmission routes of KSHV and treatment methods of KS.
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