原发性卵巢类癌合并肝转移一例  

A Case Report of Primary Ovarian Carcinoid with Liver Metastases

作　　者：张婷婷[1] 俞萍源 陈曦[1] 郑铎 杨永秀[2] ZHANG Ting-ting;YU Ping-yuan;CHEN Xi;ZHENG Duo;YANG Yong-xiu(The First School of Clinical Medicine of Lanzhou University,Lanzhou 730030,China;The First Hospital of Lanzhou University,Lanzhou 730030,China)

机构地区：[1]兰州大学第一临床医学院,730030 [2]兰州大学第一医院

出　　处：《国际妇产科学杂志》2024年第4期380-383,共4页Journal of International Obstetrics and Gynecology

基　　金：兰州大学医学科研创新能力提升项目(lzuyxcx-2022-200)。

摘　　要：原发性卵巢类癌是一种罕见的神经内分泌肿瘤,大多数患者无特异性表现,诊断主要依靠组织病理学检查。现报告1例原发性卵巢非典型类癌,患者因腹围增加2年、发现盆腔巨大肿物3 d就诊,盆腔磁共振成像(magnetic resonance imaging,MRI)提示腹、盆腔内巨大囊实性异常强化肿物,肝脏及右侧腹膜后异常强化结节及软组织肿物,予以卵巢恶性肿瘤全面分期术+肝脏表面活检术,根据术后病理检查结果诊断为卵巢非典型类癌Ⅳ期(G2T3cN1bM1b)合并肝转移、腹膜后转移,术后化疗6个周期,术后1年余复发。结合此病例讨论并复习相关文献,总结原发性卵巢类癌的临床特点、组织病理学表现、诊断、治疗及预后,旨在提高临床医师对原发性卵巢类癌的认识,为此类疾病的临床诊治提供参考。Primary ovarian carcinoid tumor is a rare neuroendocrine tumor with no specific manifestations in most patients,and the diagnosis mainly relies on histopathological examination.A case of primary ovarian atypical carcinoid tumor was reported.The patient was admitted to the clinic on the basis of an increase in abdominal circumference for 2 years and discovery of a huge pelvic mass on the third day of treatment,and the pelvic magnetic resonance imaging(MRI) showed a huge cystic solid abnormally enhancing mass in the abdomen and pelvis cavities,and abnormally reinforcing nodules in the liver and right retroperitoneum as well as a soft tissue mass,so she was treated with a comprehensive staging operation for malignant tumor of the ovary and a biopsy of the surface of liver,and was diagnosed as ovarian atypical carcinoid tumor at stage Ⅳ(G2T3cN1bM1b) based on the results of the postoperative examination combined with liver metastasis and retroperitoneal metastasis,6 cycles of postoperative chemotherapy,recurrence more than 1 year after surgery.With the discussion of this case and review of related literature,the clinical features,histopathological manifestations,diagnosis,treatment and prognosis of primary ovarian carcinoid tumor are summarized,aiming to improve the clinicians′ understanding of primary ovarian carcinoid tumor,and to provide reference for the clinical diagnosis and treatment of this kind of disease.

关 键 词：卵巢肿瘤 类癌瘤 神经内分泌瘤 肿瘤转移 病例报告 

分 类 号：R737.31[医药卫生—肿瘤]