疼痛性颞下颌关节紊乱病药物治疗的现状与研究进展  

Current Status and Progress of Drug Therapy for Painful Temporomandibular Disorders

作　　者：周燕丽 刘继红[1] ZHOU Yanli;LIU Jihong(Department of Stomatology,Hangzhou Xiaoshan Hospital of Traditional Chinese Medicine/Jiangnan Hospital Affiliated to Zhejiang Chinese Medical University,Hangzhou 311200,China)

机构地区：[1]杭州市萧山区中医院浙江中医药大学附属江南医院口腔科,杭州311200

出　　处：《医学综述》2024年第18期2261-2265,共5页Medical Recapitulate

基　　金：杭州市医药卫生科技项目(B20240165)。

摘　　要：颞下颌关节紊乱病(TMD)是一组涉及口颌面肌肉、颞下颌关节及其相关附属结构的咀嚼系统疾病,包括关节疾病和疼痛性疾病两类。药物治疗是疼痛性TMD治疗的重要环节。非甾体抗炎药、玻璃酸钠、硫酸氨基葡萄糖等关节保护药物已广泛应用于临床,精神类药物、阿片类镇痛药、肌肉松弛药等临床应用需要严格把握适应证,富血小板血浆、高渗葡萄糖、几丁壳、臭氧等新型药物的临床应用则相对较少,且仍处于研究阶段。因此,全面了解疼痛性TMD药物治疗的现状与研究进展,可以为疼痛性TMD的治疗提供新思路。Temporomandibular disorders(TMD)are a group of masticatory system diseases involving the oral and maxillofacial muscles,temporomandibular joint and related accessory structures,categorized into joint diseases and pain diseases.Drug therapy is an important part of the treatment of painful TMD.The nonsteroidal anti-inflammatory drugs,sodium hyaluronate,joint protective drugs such as glucosamine sulfate have been widely applied in the clinical practice,while the clinical applications of psychotropic drugs,opioid analgesics,and muscle relaxants need to strictly control the indications.The clinical application of new drugs such as platelet-rich plasma,hypertonic glucose,chitin,ozone etc.is relatively limited and still in the research stage.Therefore,a comprehensive understanding of the current status and research progress of drug therapy for painful TMD can provide new ideas for the treatment of painful TMD.

关 键 词：颞下颌关节紊乱病 口颌面疼痛 药物治疗 

分 类 号：R781[医药卫生—口腔医学]