双侧卵巢良性肿瘤腹腔镜剥除术后卵巢储备功能与子宫内膜容受性的相关性  

Correlation between the values of ovarian reserve function indicators of patients after laparoscopic bilateral oophorocystectomy of patients with ovarian benign tumors and the values of their endometrial receptivity indicators

作　　者：何英 罗寿召 HE Ying;LUO Shouzhao(Neijiang Hospital of Traditional Chinese Medicine,Neijiang,Sichuan Province,641000)

机构地区：[1]四川省内江市中医医院,641000

出　　处：《中国计划生育学杂志》2024年第8期1874-1877,共4页Chinese Journal of Family Planning

基　　金：四川省卫生健康科研课题(19PJ220)。

摘　　要：目的:探究双侧卵巢良性肿瘤腹腔镜剥除术后患者卵巢储备功能恢复情况及与子宫内膜容受性指标相关性。方法:回顾性收集2018年9月-2021年11月本院行腹腔镜肿瘤剥除术的双侧卵巢良性肿瘤患者62例临床资料,比较术前及术后6个月患者月经第2~3天卵巢储备功能指标[血清抗苗勒氏管激素(AMH)、基础窦卵泡数(AFC)、血清抑制素B(INHB)],基础性激素水平[卵泡刺激素(FSH)、黄体生成激素(LH)、雌二醇(E_(2))],子宫内膜容受性[子宫螺旋动脉血流阻力指数(RI)、子宫内膜厚度、子宫螺旋动脉血流搏动指数(PI)],采用Pearson相关性分析患者术后子宫内膜容受性指标与卵巢储备功能指标的相关性。结果:术后6个月,子宫内膜异位囊肿、黏液性/浆液性囊腺瘤患者血清AMH、INHB及AFC水平均低于术前(P<0.05),成熟性畸胎瘤患者AFC水平低于术前(P<0.05),AMH、INHB水平与术前无差异(P>0.05);患者血清FSH、E_(2)、RI、PI水平均低于术前,LH水平、子宫内膜厚度高于术前(均P<0.05);Pearson相关性分析显示,患者术后AMH、AFC、INHB与RI、PI水平均呈正相关,与子宫内膜厚度呈负相关(均P<0.05)。结论:双侧卵巢良性肿瘤患者行腹腔镜肿瘤剥除术后,卵巢储备功能指标与子宫内膜容受性指标具有相关性,可为术后生育评估提供临床指导。Objective:To explore the correlation between the values of ovarian reserve function indicators of patients with ovarian benign tumors after laparoscopic bilateral oophorocystectomy and the values of their endometrial receptivity indicators.Methods:The clinical data of 62 patients with ovarian benign tumors after laparoscopic bilateral oophorocystectomy from September 2018 to November 2021 were selected in this study.The values of ovarian reserve function indicators,such as the serum anti-Mullerian hormone(AMH)level,the baseline antral follicle count(AFC)and the serum inhibin B(INHB)level,the levels of basal sex hormones,such as follicle-stimulating hormone(FSH),luteinizing hormone(LH)and estradiol(E_(2)),and the values of endometrial receptivity indicators,such as flow resistance index(RI)and pulsatility index(PI)of uterine spiral arteries,and endometrial thickness,of the patients on the 2nd to 3rd day of the menstruation were compared between before surgery and in the 6th month after surgery.Pearson correlation analysis was used to evaluate the correlation between the values of the endometrial receptivity indicators of the patients after surgery and the values of their ovarian reserve function indicators.Results:The serum levels of AMH and INHB,and the AFC of the patients with endometrioma or mucinous/serous cystadenoma in the 6th month after surgery were significantly lower than those before operation surgery(P<0.05).The AFC of the patients with mature teratoma in the6th month after surgery was significantly lower than that before surgery(P<0.05),but there was no significant difference in the AMH and INHB levels of the patients between in the 6th month after surgery and before surgery(P>0.05).The levels of serum FSH,E_(2),RI and PI of the patients in the 6th month after surgery were significantly higher than those before surgery(all P<0.05).Pearson correlation analysis showed that the AMH and INHB levels,and the AFC of the patients after surgery were positively correlated with their RI and PI values,and were ne

关 键 词：双侧卵巢良性肿瘤 腹腔镜肿瘤剥除术 卵巢储备功能 子宫内膜容受性 相关性 

分 类 号：R737.31[医药卫生—肿瘤]