Insights into Euphorbia diversity: Probing the contrasts between Euphorbia fischeriana Steud and Euphorbia ebracteolata Hayata  

作　　者：Kaicheng Du Yi Zhang Lei Sun Muke Tao Tiantian Zuo Yumeng Wang Zhengfeng Zhang Dali Meng 

机构地区：[1]School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang,110016,China [2]NMPA Key Laboratory for Quality Monitoring of Narcotic Drugs and Psychotropic Substances,Chongqing Institute for Food and Drug Control,Chongqing,401121,China [3]National Institutes for Food and Drug Control,Beijing,100050,China

出　　处：《Journal of Pharmaceutical Analysis》2024年第5期775-779,共5页药物分析学报（英文版）

基　　金：supported by the National Natural Science Foundation of China(Grant No.:81573694);the Science Foundation of the Educational Department of Liaoning Province,China(Grant No.:LJKZ0920)。

摘　　要：In traditional Chinese medicine(TCM),Euphorbia fischeriana Steud(E.fischeriana)and Euphorbia ebracteolata Hayata(E.ebracteolata),commonly referred to as“Langdu”,are widely extensively utilized for treating lymphatic tuberculosis and ringworm[1].Both plant species are perennial herbaceous plants mainly distributed in northeastern China,Mongolia,Russia(Siberia),and Republic of Korea[2].There have been many reports on the chemical constituents and pharmacological effects of the two plant species,which has made more and more researchers realize that there may be differences between E.fischeriana and E.ebracteolata.In some cases,long-term improper use of herbal medicines can even lead to life-threatening conditions[3,4].Therefore,it is essential to employ an effective technology to differentiate between these two plants based on their chemical constituents and biological activities,so as to reduce the harm caused by the mixing and misuse of medicinal materials.Therefore,the present paper describes a study of the differences between E.ebracteolata and E.fischeriana,using untargeted plant metabolomics and biological activity evaluations.This study aims to provide valuable insight into their equivalence and potential interchangeability in TCM and clinical medication.

关 键 词：EUPHORBIA Siberia NORTHEASTERN 

分 类 号：R914[医药卫生—药物化学]