烟雾血管病与免疫相关疾病  

Moyamoya Angiopathy and Immune-Related Diseases

作　　者：汪敏杰 韩聪 段炼 WANG Minjie;HAN Cong;DUAN Lian(Department of Neurosurgery,The First Medical Center of Chinese PLA General Hospital,Beijing 100039,China;Department of Neurosurgery,The Fifth Medical Center of Chinese PLA General Hospital,Beijing 100071,China)

机构地区：[1]中国人民解放军总医院第一医学中心神经外科医学部,北京100039 [2]中国人民解放军总医院第五医学中心神经外科

出　　处：《中国卒中杂志》2024年第7期746-754,共9页Chinese Journal of Stroke

摘　　要：烟雾血管病是一类病因不明的颅内大动脉闭塞性疾病,主要表现为颈内动脉系统慢性狭窄、闭塞和异常血管网的形成。临床和流行病学研究发现,烟雾血管病患者具有较高的免疫相关疾病患病率,提示免疫因素在烟雾血管病的发生、发展中扮演了重要角色。本文旨在对烟雾血管病与感染、血管炎及自身免疫性疾病等免疫相关疾病的相关性研究展开综述,探讨免疫相关疾病参与烟雾血管病发病的潜在机制。Moyamoya angiopathy(MMA)is an intracranial large artery occlusive disease of unknown etiology,characterized by chronic stenosis/occlusion of the internal carotid artery system and the formation of abnormal vascular networks.Clinical and epidemiological studies have demonstrated that patients with MMA have a higher prevalence of immune-related diseases,suggesting that immune factors play an important role in the occurrence and progression of MMA.This paper aims to review the correlation between MMA and immune-related diseases such as infections,vasculitis,and autoimmune diseases,and explore the potential mechanisms of immune-related diseases involved in the pathogenesis of MMA.

关 键 词：烟雾血管病 感染 炎症 自身免疫性疾病 

分 类 号：R74[医药卫生—神经病学与精神病学]