100例急性早幼粒细胞白血病临床特征和血常规及散点图分析  

Analysis on clinical characteristics,blood routine and scatter plot of100 cases of acute promyelocytic leukemia

作　　者：姚昔友 陈穆群 尹霜梅 朱莹 王进[1] YAO Xiyou;CHEN Muqun;YIN Shuangmei;ZHU Ying;WANG Jin(Department of Clinical Laboratory,Yuxi People's Hospital/Sixth Affiliated Hospital of Kunming Medical University,Yuxi Yunnan 653100,China)

机构地区：[1]玉溪市人民医院/昆明医科大学第六附属医院医学检验科,云南玉溪653100

出　　处：《云南医药》2024年第4期43-46,共4页Medicine and Pharmacy of Yunnan

摘　　要：目的通过100例APL的临床特征和血常规及散点图分析,警示血常规报告审核人员及时进行显微镜复检,保证异常早幼粒细胞报告的准确性与及时性。方法回顾性分析100例APL患者的临床特征、血常规及散点图特征。根据白细胞计数不同,分析散点图特征。结果APL男女发病率相当,男性略多于女性。以出血、发热、乏力为主诉就诊的占比分别为46%、20%、15%,其次为体检发现血细胞减少和肿瘤术后复查发现血常规异常,分别占比8%和5%。APL患者就诊时,82%患者白细胞异常,82%患者存在不同程度的贫血,95%患者血小板降低,仅3%患者就诊时未在外周血发现异常早幼粒细胞。白细胞相近的APL患者,血常规散点图较一致。结论通过患者就诊的主诉、血常规结果和散点图指导检验人员镜检时寻找异常早幼粒细胞,为APL的快速诊断提供技巧。Objective Through the analysis of clinical characteristics,blood routine and scatter plot of 100 cases of APL,the writer warmed the reviewers of blood routine reports to conduct timely microscopic reexamination to ensure the accuracy and timeliness of abnormal promyelocyte report.Methods A retrospective analysis was conducted on the clinical features,blood routine and scatter plot features of 100 APL patients.Analyzed scatter plot features based on different white blood cell counts.Results The incidence of APL was similar between men and women,with slightly more men than women.The main complaints of bleeding,fever and fatigue accounted for 46%,20%and 15%respectively.Followed by decreased blood cells found during physical examination and abnormal blood routine found in tumor reexamination after tumor surgery,accounting for 8%and 5%respectively.At the time of treatment for APL patients,82%patients had abnormal white blood cells,82%had varying degrees of anemia,95%had low platelet count,and only 3%had no abnormal promyelocytes in peripheral blood at the time of treatment.In APL patients with similar white blood cells,the blood routine scatter plots were more consistent.Conclusions Through the patient s chief complaint,blood routine results and scatter plot guidance,laboratory personnel can be guided to find abnormal promyelocytes during microscopic examination,and providing skills for the rapid diagnosis of APL.

关 键 词：急性早幼粒细胞白血病 临床特征 血常规 散点图 

分 类 号：R733.71[医药卫生—肿瘤]