TFF3对恶性肿瘤发生发展作用的研究进展  

Research progresses on the effect of TFF3 on the genesisand development of malignant tumors

作　　者：陈丽瑶(综述) 钱海洪 王华(审校)[1] CHEN Liyao;QIAN Haihong;Wang Hua(Tumour Center,Yuxi People's Hospital/Sixth Affiliated Hospital of Kunming Medical University,Yuxi Yunnan 653100,China)

机构地区：[1]玉溪市人民医院/昆明医科大学第六附属医院肿瘤中心,云南玉溪653100

出　　处：《云南医药》2024年第4期90-93,共4页Medicine and Pharmacy of Yunnan

基　　金：云南省教育厅科学基金研究项目(2023J0311)。

摘　　要：TFF3是一类小分子多肽,是三叶肽家族的成员之一。在哺乳动物体内具有调控黏膜保护与修复、肿瘤抑制、信号传导及调节细胞凋亡等作用。近年来,TFF3在肿瘤的研究中日益受到关注,本文将对TFF3的分子结构、生理功能及在肿瘤发生发展中的作用进行综述。TFF3 is a small molecule polypetide and a member of the trefoil peptide family.It plays a key role in regulating mucosal protection and repair recovery in mammals,tumor suppression,signal transduction and regulating cell apoptosis.In recent years,TFF3 has attracted more and more attention in tumor related researches.This article reviews the molecular structure,physiological function and role of TFF3 on in the genesis and development of tumors.

关 键 词：三叶因子3 恶性肿瘤 作用机制 预后 

分 类 号：R730.2[医药卫生—肿瘤]