经腹入路与经后腹腔入路腹腔镜肾部分切除术治疗T1aN0M0期肾癌的效果分析  

Effect analysis of transabdominal approach and retroperitoneal approach laparoscopic partial nephrectomy in the treatment of stage T1aN0M0 renal carcinoma

作　　者：梁杰[1] 赵炎[1] 董宇宁 戚景光[1] 曹敬毅[1] LIANG Jie;ZHAO Yan;DONG Yu'ning;QI Jingguang;CAO Jingyi(Department of Urology,Xuzhou Cancer Hospital,Xuzhou,221005,Jiangsu,China)

机构地区：[1]徐州市肿瘤医院泌尿外科,江苏徐州221005

出　　处：《大医生》2024年第15期28-31,共4页Doctor

摘　　要：目的对比经腹入路与经后腹腔入路腹腔镜肾部分切除术(LPN)治疗T1aN0M0期肾癌的效果,为临床提供参考。方法回顾性分析2021年1月至2024年1月徐州市肿瘤医院收治的100例进行LPN治疗的T1aN0M0肾癌患者的临床资料,根据手术方法的不同分为对照组(50例,接受经腹入路LPN治疗)和观察组(50例,接受经后腹腔入路LPN治疗)。比较两组患者围术期指标水平、应激指标水平和术后并发症发生情况。结果观察组患者手术时间与术后住院时间均短于对照组(均P<0.05);两组患者手术成功率、术中出血量比较,差异均无统计学意义(均P>0.05)。术后1 d,两组患者丙二醛(MDA)、皮质醇(Cor)水平均高于术前,但观察组均低于对照组(均P<0.05)。两组患者术后并发症总发生率比较,差异无统计学意义(P>0.05)。结论与经腹入路相比,经后腹腔入路LPN治疗T1aN0M0期肾癌在缩短手术时间和术后住院时间及减轻应激反应等方面具有优势,值得临床应用。Objective To compare the effect of transabdominal approach and retroperitoneal approach laparoscopic partial nephrectomy(LPN)in the treatment of stage T1aN0M0 renal carcinoma,and to provide clinical reference.Methods The clinical data of 100 patients with T1aN0M0 renal carcinoma who underwent LPN in Xuzhou Cancer Hospital from January 2021 to January 2024 were retrospectively analyzed and divided into the control group(50 cases,LPN was treated by transabdominal approach)and the observation group(50 cases,LPN was treated by retroperitoneal approach)according to the different points of surgical method.The levels of perioperative indexes,stress response indexes and the occurrence of postoperative complications were compared between the two groups.Results The operation time and postoperative hospitalization time in the observation group were shorter than those in the control group(all P<0.05).There was no significant difference in the success rate of operation and the amount of blood loss during operation between the two groups(all P>0.05).On 1st day after surgery,the levels of malondialdehyde(MDA)and cortisol(Cor)in two groups were higher than before surgery,but the observation group was lower than control group(all P<0.05).There was no significant difference in the total incidence of postoperative complications between the two groups(P>0.05).Conclusion Compared with transabdominal approach LPN,retroperitoneal approach LPN has advantages in the treatment of stage T1aN0M0 renal carcinoma in terms of operation time,postoperative hospitalization time and stress response reduction,and is worthy of clinical application.

关 键 词：经腹入路 经后腹腔入路 腹腔镜肾部分切除术 T1aN0M0期肾癌 

分 类 号：R737.11[医药卫生—肿瘤]