近端胃切除术后胃食管反流病的研究进展  

Research progress of gastroesophageal reflux disease after proximal gastrectomy

作　　者：张家萌 马宇 张震[2] 苗雨[3] 张飞雄[3] Zhang Jiameng;Ma Yu;Zhang Zhen;Miao Yu;Zhang Feixiong(General Hospital of Ningxia Medical University(the First School of Clinical Medicine),Yinchuan 750004,China;Department of Geriatrics and Specialty Medicine,General Hospital of Ningxia Medical University,Yinchuan 750004,China;Department of Gastroenterology,General Hospital of Ningxia Medical University,Yinchuan 750004,China)

机构地区：[1]宁夏医科大学总医院(第一临床医学院),银川750004 [2]宁夏医科大学总医院老年与特需医学科,银川750004 [3]宁夏医科大学总医院消化内科,银川750004

出　　处：《中国医药》2024年第9期1411-1415,共5页China Medicine

基　　金：宁夏自然科学基金(2023AAC03517、2023AAC03529)。

摘　　要：胃食管反流病(GERD)是一种常见的消化系统疾病,其病因复杂且反复发作,给临床医师带来了很大的困扰。近端胃切除术作为一种治疗胃癌等疾病的手术方法,破坏了贲门及周边的生理结构,可能导致术后残胃反酸、反流现象的发生,从而引发GERD。这种情况严重影响了患者的生活质量。本文主要对近端胃切除术后GERD的发病机制、治疗方法以及抗反流术式的进展进行了总结,旨在为近端胃切除术后GERD治疗方案的选择提供参考依据。Gastroesophageal reflux disease(GERD)is a common digestive system disease with complex etiology and recurrent episodes,which has brought great trouble to clinicians.As a surgical method for the treatment of gastric cancer and other diseases,proximal gastrectomy destroys the physiological structure of the cardia and its surrounding area,which may lead to the occurrence of acid reflux and reflux phenomenon in the residual stomach after surgery,which may cause GERD.This situation seriously affects the quality of life of patients.This article mainly summarizes the pathogenesis,treatment methods and the progress of anti-reflux surgery for GERD after proximal gastrectomy,aiming to provide a reference for the selection of treatment options for GERD after proximal gastrectomy.

关 键 词：近端胃切除术 胃食管反流病 药物治疗 替代疗法 抗反流术 

分 类 号：R57[医药卫生—消化系统]