机构地区:[1]安徽中医药大学第二附属医院脑病一科,安徽省合肥市230061
出 处:《实用心脑肺血管病杂志》2024年第9期86-90,共5页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
基 金:安徽省中医药传承创新科研项目(2020cczd04)。
摘 要:目的分析俞募配穴针刺联合中药穴位贴敷治疗脑卒中后肺部感染的效果。方法选取2021年4月—2024年3月安徽中医药大学第二附属医院脑病一科收治的脑卒中后肺部感染患者64例为研究对象。采用随机数字表法将患者分为对照组(32例)、观察组(32例)。对照组接受西医常规治疗,观察组在对照组的基础上接受俞募配穴针刺联合中药穴位贴敷治疗,连续治疗14 d。比较两组基本资料和治疗前后痰量、外周血炎症指标[包括C反应蛋白(CRP)、降钙素原(PCT)、白介素6(IL-6)、中性粒细胞与淋巴细胞比值(NLR)]、临床肺部感染评分(CPIS)及抗生素使用时间、临床疗效。结果观察组1例患者治疗期间因依从性差而被剔除。治疗后,观察组患者痰量少于对照组(P<0.05);对照组、观察组治疗后痰量分别少于本组治疗前(P<0.05)。治疗后,观察组外周血CRP、PCT、IL-6、NLR低于对照组(P<0.05);对照组、观察组治疗后外周血CRP、PCT、IL-6、NLR分别低于本组治疗前(P<0.05)。治疗后,观察组CPIS低于对照组(P<0.05);对照组、观察组治疗后CPIS分别低于本组治疗前(P<0.05)。观察组抗生素使用时间短于对照组(P<0.05)。观察组临床疗效优于对照组(P<0.05)。结论俞募配穴针刺联合中药穴位贴敷可有效减少脑卒中后肺部感染患者痰量,抑制炎症反应,改善肺部感染症状,缩短抗生素使用时间,提高临床疗效。Objective To analyse the effect of acupuncture at back-Shu and front-Mu acupoints combined with acupoint application of Chinese medicine in the treatment of pulmonary infection after stroke.Methods A total of 64 patients with pulmonary infection after stroke admitted to Department of Encephalopathy,the Second Affiliated Hospital of Anhui University of Chinese Medicine from April 2021 to March 2024 were selected as the research subjects.The patients were divided into control group(32 cases)and observation group(32 cases)using random number table method.The control group received conventional Western medicine treatment,while the observation group received acupuncture at back-Shu and front-Mu acupoints combined with acupoint application of Chinese medicine on the basis of the control group.Both groups were treated continuously for 14 days.The basic data,and sputum volume,peripheral blood inflammatory indicators[including C-reactive protein(CRP),procalcitonin(PCT),interleukin 6(IL-6),neutrophil to lymphocyte ratio(NLR)],Clinical Pulmonary Infection Score(CPIS)and antibiotic use time before and after treatment and clinical efficacy were compared between the two groups.Results One patient in the observation group was excluded from this study due to poor compliance during treatment.After treatment,the sputum volume of the observation group was less than that of the control group(P<0.05);the sputum volume of the control group and observation group after treatment was less than that before treatment respectively(P<0.05).After treatment,the peripheral blood levels of CRP,PCT,IL-6,and NLR in the observation group were lower than those in the control group(P<0.05);the peripheral blood levels of CRP,PCT,IL-6,and NLR in the control group and observation group after treatment were lower than those before treatment respectively(P<0.05).After treatment,the CPIS of the observation group was lower than that of the control group(P<0.05);the CPIS of the control group and observation group after treatment was lower than that before tr
分 类 号:R743[医药卫生—神经病学与精神病学]
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